The conformational changes of aspartate induced by increasing ionic strength were investigated by means of NMR spectroscopy. The effects of Li, Na, K and Cs chlorides in basic solutions show a relative stabilization of the two conformers with gauche carboxylates at the expense of the anti conformer. A significant quantitative difference was found between Na+ and K+. The changes observed in neutral solutions, although larger than those in basic solutions, are dominated by the zwitterion interaction.
|Original language||English (US)|
|Number of pages||12|
|Journal||Advances in Molecular Relaxation and Interaction Processes|
|State||Published - Sep 1982|