TY - JOUR
T1 - Correction to
T2 - Helminth colonization is associated with increased diversity of the gut microbiota (PLoS Neglected Tropical Diseases)
AU - Lee, Soo Ching
AU - Tang, Mei San
AU - Lim, Yvonne A.L.
AU - Choy, Seow Huey
AU - Kurtz, Zachary D.
AU - Cox, Laura M.
AU - Gundra, Uma Mahesh
AU - Cho, Ilseung
AU - Bonneau, Richard
AU - Blaser, Martin J.
AU - Chua, Kek Heng
AU - Loke, P’Ng
N1 - Publisher Copyright:
© 2021 Lee et al.
PY - 2014
Y1 - 2014
N2 - Explanation of the Correction provided by the authors: The authors were recently brought to attention about inconsistencies in the color-coding of helminth positive vs. helminth negative individuals between panels in Figs 1 and 2 of this publication [1]. During the process of responding to these queries, we identified mislabeling in the metadata for the analysis of the alpha diversity metric Observed Operational Taxonomic Units (OTUs), where helminth positive and helminth negative individuals were not matched to the correct values of Observed OTUs. The corrected values along with the associated helminth colonization status are presented here. There is no association between Observed OTUs and age using the corrected values, as described in the original publication (Fig 1A). However, we found that the differences in Observed OTUs between helminth positive and helminth negative individuals were statistically not significant (p = 0.73, Fig 2D, graph 1), which was different from our original report. While there was no mislabeling in the calculations of the alpha diversity metrics Faith’s Phylogenetic Diversity and Shannon index, we have re-visualized the values of these two alpha diversity metrics in similar boxplot formats for comparison. The Phylogenetic Diversity of the gut microbiota between helminth positive and helminth negative individuals was significantly different (p = 0.041, Fig 2D, graph 2), while the Shannon index of the gut microbiota between helminth positive and helminth negative individuals was statistically not significant (p = 0.303, Fig 2D, graph 3), as reported in the original publication. Values for each alpha diversity metric, along with the associated helminth status, are available in S1 File. The original publication has not been corrected online.
AB - Explanation of the Correction provided by the authors: The authors were recently brought to attention about inconsistencies in the color-coding of helminth positive vs. helminth negative individuals between panels in Figs 1 and 2 of this publication [1]. During the process of responding to these queries, we identified mislabeling in the metadata for the analysis of the alpha diversity metric Observed Operational Taxonomic Units (OTUs), where helminth positive and helminth negative individuals were not matched to the correct values of Observed OTUs. The corrected values along with the associated helminth colonization status are presented here. There is no association between Observed OTUs and age using the corrected values, as described in the original publication (Fig 1A). However, we found that the differences in Observed OTUs between helminth positive and helminth negative individuals were statistically not significant (p = 0.73, Fig 2D, graph 1), which was different from our original report. While there was no mislabeling in the calculations of the alpha diversity metrics Faith’s Phylogenetic Diversity and Shannon index, we have re-visualized the values of these two alpha diversity metrics in similar boxplot formats for comparison. The Phylogenetic Diversity of the gut microbiota between helminth positive and helminth negative individuals was significantly different (p = 0.041, Fig 2D, graph 2), while the Shannon index of the gut microbiota between helminth positive and helminth negative individuals was statistically not significant (p = 0.303, Fig 2D, graph 3), as reported in the original publication. Values for each alpha diversity metric, along with the associated helminth status, are available in S1 File. The original publication has not been corrected online.
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U2 - 10.1371/journal.pntd.0009325
DO - 10.1371/journal.pntd.0009325
M3 - Comment/debate
AN - SCOPUS:85103831319
SN - 1935-2727
VL - 8
JO - PLoS neglected tropical diseases
JF - PLoS neglected tropical diseases
IS - 5
M1 - e0009325
ER -