Correlating Enzyme Activity and Cellular Behavior

Timothy M. Dore

Research output: Contribution to journalShort surveypeer-review


A photoactivatable phosphorylation sensor used in conjunction with isoform specific inhibitors of protein kinase C enables the enzyme's activity to be monitored inside cells at specific time points during mitosis. PKCβ was found to be active before, but not after, nuclear envelope breakdown [1].

Original languageEnglish (US)
Pages (from-to)1202-1203
Number of pages2
JournalChemistry and Biology
Issue number11
StatePublished - Nov 26 2007

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry


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