Correlating Enzyme Activity and Cellular Behavior

Timothy M. Dore

doi:10.1016/j.chembiol.2007.11.001

Correlating Enzyme Activity and Cellular Behavior

Timothy M. Dore

Chemistry

Research output: Contribution to journal › Short survey › peer-review

Abstract

A photoactivatable phosphorylation sensor used in conjunction with isoform specific inhibitors of protein kinase C enables the enzyme's activity to be monitored inside cells at specific time points during mitosis. PKCβ was found to be active before, but not after, nuclear envelope breakdown [1].

Original language	English (US)
Pages (from-to)	1202-1203
Number of pages	2
Journal	Chemistry and Biology
Volume	14
Issue number	11
DOIs	https://doi.org/10.1016/j.chembiol.2007.11.001
State	Published - Nov 26 2007

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmacology
Drug Discovery
Clinical Biochemistry

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10.1016/j.chembiol.2007.11.001

Cite this

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title = "Correlating Enzyme Activity and Cellular Behavior",

abstract = "A photoactivatable phosphorylation sensor used in conjunction with isoform specific inhibitors of protein kinase C enables the enzyme's activity to be monitored inside cells at specific time points during mitosis. PKCβ was found to be active before, but not after, nuclear envelope breakdown [1].",

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year = "2007",

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JO - Chemistry and Biology

JF - Chemistry and Biology

IS - 11

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Correlating Enzyme Activity and Cellular Behavior

Abstract

ASJC Scopus subject areas

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