Cross-dressing proteins by olefin metathesis

Research output: Contribution to journalShort survey

Abstract

Chemists have established numerous methods for performing protein conjugations, but metathesis catalysts have largely remained absent from this toolkit. Evidence that proteins bearing allylsulfides undergo cross-metathesis with chosen alkenes in aqueous conditions will allow chemists to harness the power of metathesis catalysts for modifying biomolecules and other water-soluble compounds.

Original languageEnglish (US)
Pages (from-to)527-528
Number of pages2
JournalNature Chemical Biology
Volume4
Issue number9
DOIs
StatePublished - Sep 2008

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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