Cross-dressing proteins by olefin metathesis

Research output: Contribution to journalShort surveypeer-review

Abstract

Chemists have established numerous methods for performing protein conjugations, but metathesis catalysts have largely remained absent from this toolkit. Evidence that proteins bearing allylsulfides undergo cross-metathesis with chosen alkenes in aqueous conditions will allow chemists to harness the power of metathesis catalysts for modifying biomolecules and other water-soluble compounds.

Original languageEnglish (US)
Pages (from-to)527-528
Number of pages2
JournalNature Chemical Biology
Volume4
Issue number9
DOIs
StatePublished - Sep 2008

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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