@article{129ae3bd22ce4c8e9ad74252900d2d1b,
title = "Cryptochromes Interact Directly with PIFs to Control Plant Growth in Limiting Blue Light",
abstract = "Sun-loving plants have the ability to detect and avoid shading through sensing of both blue and red light wavelengths. Higher plant cryptochromes (CRYs) control how plants modulate growth in response to changes in blue light. For growth under a canopy, where blue light is diminished, CRY1 and CRY2 perceive this change and respond by directly contacting two bHLH transcription factors, PIF4 and PIF5. These factors are also known to be controlled by phytochromes, the red/far-red photoreceptors; however, transcriptome analyses indicate that the gene regulatory programs induced by the different light wavelengths are distinct. Our results indicate that CRYs signal by modulating PIF activity genome wide and that these factors integrate binding of different plant photoreceptors to facilitate growth changes under different light conditions.",
author = "Pedmale, {Ullas V.} and Huang, {Shao Shan Carol} and Mark Zander and Cole, {Benjamin J.} and Jonathan Hetzel and Karin Ljung and Reis, {Pedro A.B.} and Priya Sridevi and Kazumasa Nito and Nery, {Joseph R.} and Ecker, {Joseph R.} and Joanne Chory",
note = "Funding Information: We thank Z. Avramova, T. Yamashino, and C. Fankhauser for XTH33ox, ATHB2ox, and pin seeds; C. Lin and A. Nagatani for CRY and PHY antiserum; C. Lagarias for phycocyanobilin; Y. Jaillais, A. Seluzicki, C. Procko, and D. O{\textquoteright}Keefe for critical reading of the draft; and R. Granbom for assistance with the IAA measurements. K.L. was funded by the Swedish Governmental Agency for Innovation Systems , the Swedish Research Council , and the Marianne and Marcus Wallenberg Foundation . M.Z. was supported by DFG ( Za-730/1-1 ). J.H. was supported by the NIH ( T32GM007240 ), the Rose Hills Foundation , and the H.A. and Mary K. Chapman Charitable Trust . J.R.E. was supported by DOE ( FG02-04ER15517 ), the NSF ( MCB-1024999 ), and the Gordon and Betty Moore Foundation ( GBMF3034 ). J.C. and J.R.E. are investigators of the Howard Hughes Medical Institute. NIH grant R01-GM52413 to J.C. funded this study. Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",
year = "2016",
month = jan,
day = "14",
doi = "10.1016/j.cell.2015.12.018",
language = "English (US)",
volume = "164",
pages = "233--245",
journal = "Cell",
issn = "0092-8674",
publisher = "Cell Press",
number = "1-2",
}