@article{2756f6ffe7a9455ba88789d7d29986e4,
title = "CuI-Catalyzed Synthesis of Propargyl Hydroperoxides Using Molecular Oxygen and Hydroxylamines",
abstract = "A CuI-catalyzed oxidation of enynes using N-hydroxybenzotriazole (HOBt) or N-hydroxyphthalimide (NHPI) with molecular oxygen has been developed to yield propargyl hydroperoxides. The reaction occurs under O2 at 0°C to afford hydroperoxides in 1-4 h. This method provides an alternative to H2O2 or tBuOOH by using molecular oxygen as the source of oxygen atoms. The resulting hydroperoxides can be protected prior to purification and converted into alkoxyamines upon treatment with hydrazine.",
keywords = "Enynes, Oxidation, Peroxides",
author = "Miner, {Matthew R.} and Woerpel, {K. A.}",
note = "Funding Information: This research was supported by the National Science Foundation (CHE-0848121). M. R. M. acknowledges a Margaret Strauss Kramer Fellowship from the NYU Department of Chemistry. The Bruker Avance 400 MHz spectrometer was acquired through the support of the National Science Foundation (CHE-01162222). We thank Dr. Chin Lin (NYU) for assistance with NMR spectroscopy and mass spectrometry. We also thank the Molecular Design Institute of NYU for purchasing a single-crystal diffractometer, and Dr. Chunhua Hu (NYU) for his assistance with data collection and structure determination. Publisher Copyright: Copyright {\textcopyright} 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",
year = "2016",
month = apr,
doi = "10.1002/ejoc.201600038",
language = "English (US)",
volume = "2016",
pages = "1860--1866",
journal = "European Journal of Organic Chemistry",
issn = "1434-193X",
publisher = "Wiley-VCH Verlag",
number = "10",
}