Cytoskeletal Chirality: Swirling Cells Tell Left from Right

Alex Mogilner, Ben Fogelson

Research output: Contribution to journalShort surveypeer-review

Abstract

Summary A new study reports that dynamic actin fibers in cells on circular islands self-organize into a swirling counter-clockwise pattern and describes a basic cytoskeletal mechanism for the establishment of left-right asymmetry that is based on myosin contraction and twisting of the formin-actin filament.

Original languageEnglish (US)
Article number11982
Pages (from-to)R501-R503
JournalCurrent Biology
Volume25
Issue number12
DOIs
StatePublished - Jun 15 2015

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology
  • General Agricultural and Biological Sciences

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