Daily Factors Associated with Antiretroviral Therapy Adherence Among Young Latino Sexual Minority Men with HIV: A 28-Day Daily Diary Study

Diana M. Sheehan, Daisy Ramírez-Ortiz, Tendai Gwanzura, Patrice S. Lewis, Melissa M. Ertl, Dustin T. Duncan, Dallas Swendeman, Miguel Muñoz-Laboy, Jessy G. Devieux, Mary Jo Trepka

Research output: Contribution to journalArticlepeer-review

Abstract

We assessed the relationship between same-day and next-day antiretroviral therapy (ART) adherence and adherence self-efficacy, daily routine disruptions, mental health, sleep, social support, substance use, and contextual factors in an ecological momentary assessment (EMA) study. Twenty-eight days of data from a convenience sample of 54 18-34-year-old young Latino sexual minority men (YLSMM) was used in generalized mixed models. Participants adhered to ARTs on 96% of 1,306 person-days. Daily motivation to stay healthy, to prevent HIV transmission, and ART self-efficacy were associated with same-day adherence. Routine disruptions, poor sleep, and drug use were associated with same-day non-adherence. Stress was associated with next-day non-adherence, and increased routine disruptions with non-adherence. Findings suggest an opportunity to design and test innovative interventions for YLSMM to improve ART adherence that increase daily adherence motivation and self-efficacy and provide real-time assistance during changes in routine, poor sleep, drug use, and stress.

Original languageEnglish (US)
JournalAIDS and Behavior
DOIs
StateAccepted/In press - 2025

Keywords

  • Adherence
  • Antiretroviral therapy
  • Ecological momentary assessment
  • Human immunodeficiency virus
  • Latinos

ASJC Scopus subject areas

  • Social Psychology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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