Daily short message service surveys to measure sexual behavior and pre-exposure prophylaxis use among kenyan men and women

Kathryn Curran; Nelly R. Mugo; Ann Kurth; Kenneth Ngure; Renee Heffron; Deborah Donnell; Connie Celum; Jared M. Baeten

doi:10.1007/s10461-013-0510-4

Daily short message service surveys to measure sexual behavior and pre-exposure prophylaxis use among kenyan men and women

Kathryn Curran, Nelly R. Mugo, Ann Kurth, Kenneth Ngure, Renee Heffron, Deborah Donnell, Connie Celum, Jared M. Baeten

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Abstract

Pre-exposure prophylaxis (PrEP) is a novel HIV prevention strategy which requires high adherence. We tested the use of daily short message service (i.e., SMS/text message) surveys to measure sexual behavior and PrEP adherence in Kenya. Ninety-six HIV-uninfected adult individuals, taking daily oral PrEP in a clinical trial, received daily SMS surveys for 60 days. Most participants (96.9 %) reported taking PrEP on ≥80 % days, but 69.8 % missed at least one dose. Unprotected sex was reported on 4.9 % of days; however, 47.9 % of participants reported unprotected sex at least once. Unprotected sex was not correlated with PrEP use (OR = 0.95). Participants reporting more sex were less likely to report PrEP non-adherence and those reporting no sex were most likely to report missing a PrEP dose (adjusted OR = 1.87). PrEP adherence was high, missed doses were correlated with sexual abstinence, and unprotected sex was not associated with decreased PrEP adherence.

Original language	English (US)
Pages (from-to)	2977-2985
Number of pages	9
Journal	AIDS and Behavior
Volume	17
Issue number	9
DOIs	https://doi.org/10.1007/s10461-013-0510-4
State	Published - Nov 2013

Keywords

Adherence
HIV prevention
HIV serodiscordant couples
Pre-exposure prophylaxis
Sexual behavior

ASJC Scopus subject areas

Social Psychology
Public Health, Environmental and Occupational Health
Infectious Diseases

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10.1007/s10461-013-0510-4

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title = "Daily short message service surveys to measure sexual behavior and pre-exposure prophylaxis use among kenyan men and women",

abstract = "Pre-exposure prophylaxis (PrEP) is a novel HIV prevention strategy which requires high adherence. We tested the use of daily short message service (i.e., SMS/text message) surveys to measure sexual behavior and PrEP adherence in Kenya. Ninety-six HIV-uninfected adult individuals, taking daily oral PrEP in a clinical trial, received daily SMS surveys for 60 days. Most participants (96.9 %) reported taking PrEP on ≥80 % days, but 69.8 % missed at least one dose. Unprotected sex was reported on 4.9 % of days; however, 47.9 % of participants reported unprotected sex at least once. Unprotected sex was not correlated with PrEP use (OR = 0.95). Participants reporting more sex were less likely to report PrEP non-adherence and those reporting no sex were most likely to report missing a PrEP dose (adjusted OR = 1.87). PrEP adherence was high, missed doses were correlated with sexual abstinence, and unprotected sex was not associated with decreased PrEP adherence.",

keywords = "Adherence, HIV prevention, HIV serodiscordant couples, Pre-exposure prophylaxis, Sexual behavior",

author = "Kathryn Curran and Mugo, {Nelly R.} and Ann Kurth and Kenneth Ngure and Renee Heffron and Deborah Donnell and Connie Celum and Baeten, {Jared M.}",

note = "Funding Information: Acknowledgments We thank the study participants, Partners PrEP Study staff in Thika, Kenya, and our technical partner Dimagi for all their time and efforts. The National Institutes of Health (R21 NR012663) and the Bill and Melinda Gates Foundation (Grant OPP47674) provided financial support for this study. KC was a scholar in the International AIDS Research and Training Program, supported by the Fogarty International Center (D43 TW000007), and in the University of Washington STD/AIDS Research Training Program (T32 AI007140).",

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doi = "10.1007/s10461-013-0510-4",

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AU - Ngure, Kenneth

AU - Heffron, Renee

AU - Donnell, Deborah

AU - Celum, Connie

AU - Baeten, Jared M.

N1 - Funding Information: Acknowledgments We thank the study participants, Partners PrEP Study staff in Thika, Kenya, and our technical partner Dimagi for all their time and efforts. The National Institutes of Health (R21 NR012663) and the Bill and Melinda Gates Foundation (Grant OPP47674) provided financial support for this study. KC was a scholar in the International AIDS Research and Training Program, supported by the Fogarty International Center (D43 TW000007), and in the University of Washington STD/AIDS Research Training Program (T32 AI007140).

PY - 2013/11

Y1 - 2013/11

N2 - Pre-exposure prophylaxis (PrEP) is a novel HIV prevention strategy which requires high adherence. We tested the use of daily short message service (i.e., SMS/text message) surveys to measure sexual behavior and PrEP adherence in Kenya. Ninety-six HIV-uninfected adult individuals, taking daily oral PrEP in a clinical trial, received daily SMS surveys for 60 days. Most participants (96.9 %) reported taking PrEP on ≥80 % days, but 69.8 % missed at least one dose. Unprotected sex was reported on 4.9 % of days; however, 47.9 % of participants reported unprotected sex at least once. Unprotected sex was not correlated with PrEP use (OR = 0.95). Participants reporting more sex were less likely to report PrEP non-adherence and those reporting no sex were most likely to report missing a PrEP dose (adjusted OR = 1.87). PrEP adherence was high, missed doses were correlated with sexual abstinence, and unprotected sex was not associated with decreased PrEP adherence.

AB - Pre-exposure prophylaxis (PrEP) is a novel HIV prevention strategy which requires high adherence. We tested the use of daily short message service (i.e., SMS/text message) surveys to measure sexual behavior and PrEP adherence in Kenya. Ninety-six HIV-uninfected adult individuals, taking daily oral PrEP in a clinical trial, received daily SMS surveys for 60 days. Most participants (96.9 %) reported taking PrEP on ≥80 % days, but 69.8 % missed at least one dose. Unprotected sex was reported on 4.9 % of days; however, 47.9 % of participants reported unprotected sex at least once. Unprotected sex was not correlated with PrEP use (OR = 0.95). Participants reporting more sex were less likely to report PrEP non-adherence and those reporting no sex were most likely to report missing a PrEP dose (adjusted OR = 1.87). PrEP adherence was high, missed doses were correlated with sexual abstinence, and unprotected sex was not associated with decreased PrEP adherence.

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Daily short message service surveys to measure sexual behavior and pre-exposure prophylaxis use among kenyan men and women

Abstract

Keywords

ASJC Scopus subject areas

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