Damage accumulation model of prosthetic heart valves in forward and reverse flow phases

Wared Alemu; Michalis Xenos; Yuefan Deng; Rui Feng; Shmuel Einav; Danny Bluestein

Damage accumulation model of prosthetic heart valves in forward and reverse flow phases

Wared Alemu, Michalis Xenos, Yuefan Deng, Rui Feng, Shmuel Einav, Danny Bluestein

Mathematics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

A highly resolved 3D geometry of a bileflet mechanical heart valve (MHV) was constructed to study the contribution of the forward and regurgitant flow phases to platelet damage. Platelet stress accumulation during repetitive passages past the valve was calculated using a damage accumulation model in pertinent trajectories. Additionally a discrete particles dynamics (DPD) multiscale modeling approach, which widely departs from the traditional continuum approach, was applied to this MHV geometry. It generated viscous blood flow velocity distributions, and is envisioned to further facilitate multiscale simulations of flow induced thrombogenicity in blood recirculating devices.

Original language	English (US)
Title of host publication	Proceedings of the ASME Summer Bioengineering Conference, SBC2008
Pages	1097-1098
Number of pages	2
Edition	PART B
State	Published - 2009
Event	10th ASME Summer Bioengineering Conference, SBC2008 - Marco Island, FL, United States Duration: Jun 25 2008 → Jun 29 2008

Publication series

Name	Proceedings of the ASME Summer Bioengineering Conference, SBC2008
Number	PART B

Other

Other	10th ASME Summer Bioengineering Conference, SBC2008
Country/Territory	United States
City	Marco Island, FL
Period	6/25/08 → 6/29/08

ASJC Scopus subject areas

Biotechnology
Bioengineering
Biomedical Engineering

Cite this

Damage accumulation model of prosthetic heart valves in forward and reverse flow phases. / Alemu, Wared; Xenos, Michalis; Deng, Yuefan et al.
Proceedings of the ASME Summer Bioengineering Conference, SBC2008. PART B. ed. 2009. p. 1097-1098 (Proceedings of the ASME Summer Bioengineering Conference, SBC2008; No. PART B).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Alemu, W, Xenos, M, Deng, Y, Feng, R, Einav, S & Bluestein, D 2009, Damage accumulation model of prosthetic heart valves in forward and reverse flow phases. in Proceedings of the ASME Summer Bioengineering Conference, SBC2008. PART B edn, Proceedings of the ASME Summer Bioengineering Conference, SBC2008, no. PART B, pp. 1097-1098, 10th ASME Summer Bioengineering Conference, SBC2008, Marco Island, FL, United States, 6/25/08.

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abstract = "A highly resolved 3D geometry of a bileflet mechanical heart valve (MHV) was constructed to study the contribution of the forward and regurgitant flow phases to platelet damage. Platelet stress accumulation during repetitive passages past the valve was calculated using a damage accumulation model in pertinent trajectories. Additionally a discrete particles dynamics (DPD) multiscale modeling approach, which widely departs from the traditional continuum approach, was applied to this MHV geometry. It generated viscous blood flow velocity distributions, and is envisioned to further facilitate multiscale simulations of flow induced thrombogenicity in blood recirculating devices.",

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AU - Xenos, Michalis

AU - Deng, Yuefan

AU - Feng, Rui

AU - Einav, Shmuel

AU - Bluestein, Danny

PY - 2009

Y1 - 2009

N2 - A highly resolved 3D geometry of a bileflet mechanical heart valve (MHV) was constructed to study the contribution of the forward and regurgitant flow phases to platelet damage. Platelet stress accumulation during repetitive passages past the valve was calculated using a damage accumulation model in pertinent trajectories. Additionally a discrete particles dynamics (DPD) multiscale modeling approach, which widely departs from the traditional continuum approach, was applied to this MHV geometry. It generated viscous blood flow velocity distributions, and is envisioned to further facilitate multiscale simulations of flow induced thrombogenicity in blood recirculating devices.

AB - A highly resolved 3D geometry of a bileflet mechanical heart valve (MHV) was constructed to study the contribution of the forward and regurgitant flow phases to platelet damage. Platelet stress accumulation during repetitive passages past the valve was calculated using a damage accumulation model in pertinent trajectories. Additionally a discrete particles dynamics (DPD) multiscale modeling approach, which widely departs from the traditional continuum approach, was applied to this MHV geometry. It generated viscous blood flow velocity distributions, and is envisioned to further facilitate multiscale simulations of flow induced thrombogenicity in blood recirculating devices.

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M3 - Conference contribution

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BT - Proceedings of the ASME Summer Bioengineering Conference, SBC2008

T2 - 10th ASME Summer Bioengineering Conference, SBC2008

Y2 - 25 June 2008 through 29 June 2008

ER -

Damage accumulation model of prosthetic heart valves in forward and reverse flow phases

Abstract

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ASJC Scopus subject areas

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