Deciding whether to go with the flow: Evaluating the merits of flow reactors for synthesis

Ryan L. Hartman, Jonathan P. McMullen, Klavs F. Jensen

Research output: Contribution to journalReview articlepeer-review

Abstract

The fine chemicals and pharmaceutical industries are transforming how their products are manufactured, where economically favorable, from traditional batchwise processes to continuous flow. This evolution is impacting synthetic chemistry on all scalesa - from the laboratory to full production. This Review discusses the relative merits of batch and micro flow reactors for performing synthetic chemistry in the laboratory. Flow or batch? The fine chemicals and pharmaceutical industries are transforming how their products are manufactured, where economically favorable, from traditional batchwise processes to continuous flow. This evolution is impacting synthetic chemistry on all scalesa - from the laboratory to full production. This Review discusses the relative merits of batch and microflow reactors for performing synthetic chemistry in the laboratory.

Original languageEnglish (US)
Pages (from-to)7502-7519
Number of pages18
JournalAngewandte Chemie - International Edition
Volume50
Issue number33
DOIs
StatePublished - Aug 8 2011

Keywords

  • continuous flow
  • flow chemistry
  • microfluidics
  • microreactors
  • synthetic chemistry

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry

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