Degradation of Structurally Defined Graphene Nanoribbons by Myeloperoxidase and the Photo-Fenton Reaction

Xiangfeng Luan, Cristina Martín, Pengfei Zhang, Qian Li, Isabella Anna Vacchi, Lucia Gemma Delogu, Yiyong Mai, Alberto Bianco

Research output: Contribution to journalArticlepeer-review


As an emerging member of the graphene family, structurally defined graphene nanoribbons (GNRs) have shown promising applications in various fields. The evaluation of the degradability of GNRs is particularly important for assessing the persistence level and risk of these materials in living organisms and the environment. However, there is a void in the study of the degradation of GNRs. Here, we report the degradation behavior of GNRs in the presence of human myeloperoxidase (hMPO) or treated with the photo-Fenton (PF) reaction. With the assistance of potassium hydroxide or imidazole, which facilitates the dispersion of GNRs in the aqueous solution, GNRs underwent only partial degradation after 25-hour incubation with hMPO, while, the PF reaction degraded GNRs almost completely after 120 hours. These results indicate that structurally precise GNRs can be efficiently degraded under suitable conditions, providing more opportunities for future applications in different fields.

Original languageEnglish (US)
Pages (from-to)18515-18521
Number of pages7
JournalAngewandte Chemie - International Edition
Issue number42
StatePublished - Oct 12 2020


  • biodegradability
  • carbon materials
  • hydroxyl radicals
  • peroxidases
  • photo-Fenton reaction

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry


Dive into the research topics of 'Degradation of Structurally Defined Graphene Nanoribbons by Myeloperoxidase and the Photo-Fenton Reaction'. Together they form a unique fingerprint.

Cite this