Denaturation and accelerated proteolysis of sizeable heme proteins by synthetic metalloporphyrins

Steven Fletcher, Andrew D. Hamilton

Research output: Contribution to journalArticlepeer-review

Abstract

A synthetic, copper porphyrin unwinds the α-helical domains of the heme proteins hemoglobin, myoglobin and cytochrome c, thereby catalysing trypsin-mediated proteolysis.

Original languageEnglish (US)
Pages (from-to)623-627
Number of pages5
JournalNew Journal of Chemistry
Volume31
Issue number5
DOIs
StatePublished - 2007

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Materials Chemistry

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