Dengue tools: Innovative tools and strategies for the surveillance and control of dengue

Annelies Wilder-Smith, Karl Erik Renhorn, Hasitha Tissera, Sazaly Abu Bakar, Luke Alphey, Pattamaporn Kittayapong, Steve Lindsay, James Logan, Christoph Hatz, Paul Reiter, Joacim Rocklöv, Peter Byass, Valérie R. Louis, Yesim Tozan, Eduardo Massad, Antonio Tenorio, Christophe Lagneau, Grégory L'Ambert, David Brooks, Johannah WegerdtDuane Gubler

Research output: Contribution to journalArticlepeer-review


Dengue fever is a mosquito-borne viral disease estimated to cause about 230 million infections worldwide every year, of which 25,000 are fatal. Global incidence has risen rapidly in recent decades with some 3.6 billion people, over half of the world's population, now at risk, mainly in urban centres of the tropics and subtropics. Demographic and societal changes, in particular urbanization, globalization, and increased international travel, are major contributors to the rise in incidence and geographic expansion of dengue infections. Major research gaps continue to hamper the control of dengue. The European Commission launched a call under the 7th Framework Programme with the title of 'Comprehensive control of Dengue fever under changing climatic conditions'. Fourteen partners from several countries in Europe, Asia, and South America formed a consortium named 'DengueTools' to respond to the call to achieve better diagnosis, surveillance, prevention, and predictive models and improve our understanding of the spread of dengue to previously uninfected regions (including Europe) in the context of globalization and climate change.The consortium comprises 12 work packages to address a set of research questions in three areas:Research area 1: Develop a comprehensive early warning and surveillance system that has predictive capability for epidemic dengue and benefits from novel tools for laboratory diagnosis and vector monitoring.Research area 2: Develop novel strategies to prevent dengue in children.Research area 3: Understand and predict the risk of global spread of dengue, in particular the risk of introduction and establishment in Europe, within the context of parameters of vectorial capacity, global mobility, and climate change.In this paper, we report on the rationale and specific study objectives of 'DengueTools'. DengueTools is funded under the Health theme of the Seventh Framework Programme of the European Community, Grant Agreement Number: 282589 Dengue Tools.

Original languageEnglish (US)
Article number17273
JournalGlobal Health Action
Issue number1
StatePublished - 2012


  • Climate change
  • Dengue
  • Dengue control
  • Dengue diagnostics
  • Early warning systems
  • Economic evaluation
  • Entomology
  • Globalization
  • Risk mapping
  • Surveillance

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health Policy


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