TY - JOUR
T1 - Depressive symptoms and their association with social determinants and chronic diseases in middle-aged and elderly Chinese people
AU - Liu, Qiaolan
AU - Cai, Hui
AU - Yang, Lawrence H.
AU - Xiang, Yong Bing
AU - Yang, Gong
AU - Li, Honglan
AU - Gao, Yu Tang
AU - Zheng, Wei
AU - Susser, Ezra
AU - Shu, Xiao Ou
N1 - Funding Information:
This study was supported by grants from the US National Institutes of Health and the Intramural Research Program of the National Institutes of Health, National Cancer Institute (R37 CA070867 and UM1 CA182910 to Wei Zheng, and R01CA082729 and UM1 CA173640 to Xiao-Ou Shu). The authors thank all participants and staff members of the Shanghai Men’s Health Study and Shanghai Women’s Health Study for their important contributions and Ms. Nan Kennedy for editing and preparing the manuscript.
Publisher Copyright:
© 2018 The Author(s).
PY - 2018/12/1
Y1 - 2018/12/1
N2 - Depression is one of the most prevalent mental disorders worldwide. Little information is available regarding association of depressive symptoms (DS) with cancer and chronic diseases among middle-aged and elderly Chinese in a population-based setting. In this study we evaluated the prevalence and examined correlates of DS in two population-based cohort studies. Included in the analyses were 103,595 people with a mean age of 61.8 years at the DS assessment. The prevalence of DS was 2.4% in men and 5.6% in women. We found elderly participants, those with lower BMI, or chronic diseases were more likely to experience DS. Having a history of stroke (odds ratio (OR) = 2.2 in men and 1.8 in women), cancer (OR = 3.3 in men and 1.9 in women), or Parkinson's disease (OR = 3.1 in men and 2.7 in women) was associated with high DS. In women, high income and high education levels were inversely related to DS. Being a single woman, long-term or heavy female smoker was associated with high prevalence of DS. High BMI was correlated with low prevalence of depression in men. Our data suggests a low prevalence of DS among middle-aged and elderly people in Shanghai, China. Age, education, income, marital status, smoking, BMI, and certain health conditions were associated with DS.
AB - Depression is one of the most prevalent mental disorders worldwide. Little information is available regarding association of depressive symptoms (DS) with cancer and chronic diseases among middle-aged and elderly Chinese in a population-based setting. In this study we evaluated the prevalence and examined correlates of DS in two population-based cohort studies. Included in the analyses were 103,595 people with a mean age of 61.8 years at the DS assessment. The prevalence of DS was 2.4% in men and 5.6% in women. We found elderly participants, those with lower BMI, or chronic diseases were more likely to experience DS. Having a history of stroke (odds ratio (OR) = 2.2 in men and 1.8 in women), cancer (OR = 3.3 in men and 1.9 in women), or Parkinson's disease (OR = 3.1 in men and 2.7 in women) was associated with high DS. In women, high income and high education levels were inversely related to DS. Being a single woman, long-term or heavy female smoker was associated with high prevalence of DS. High BMI was correlated with low prevalence of depression in men. Our data suggests a low prevalence of DS among middle-aged and elderly people in Shanghai, China. Age, education, income, marital status, smoking, BMI, and certain health conditions were associated with DS.
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U2 - 10.1038/s41598-018-22175-2
DO - 10.1038/s41598-018-22175-2
M3 - Article
C2 - 29497126
AN - SCOPUS:85042773549
SN - 2045-2322
VL - 8
JO - Scientific Reports
JF - Scientific Reports
IS - 1
M1 - 3841
ER -