Destroying retroviruses from within

Jef D. Boeke, Beatrice Hahn

Research output: Contribution to journalReview articlepeer-review


One strategy for neutralizing retroviral infectivity is to induce the incorporation of lethal fusion proteins, such as capsid protein-nuclease fusions, into the virion during the normal viral assembly process. Genes encoding such antiviral fusion proteins must be nontoxic to the host, lethal to the virus, and must be efficiently delivered to, and expressed in, appropriate target cells.

Original languageEnglish (US)
Pages (from-to)421-426
Number of pages6
JournalTrends in Microbiology
Issue number11
StatePublished - Nov 1996

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases
  • Virology


Dive into the research topics of 'Destroying retroviruses from within'. Together they form a unique fingerprint.

Cite this