Detecting DNA-Ligand Electrostatic Interactions With a FRET-Based Probe

Chandrashekhar U. Murade, George T. Shubeita

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

DNA-ligand interactions are dominated by electrostatics as DNA is a highly charged molecule at physiological conditions. Here, we present a FRET-based sensor which can optically report on these interactions between DNA and charged ligands.

Original languageEnglish (US)
Title of host publicationComputational Optical Sensing and Imaging, COSI 2022
PublisherOptica Publishing Group (formerly OSA)
ISBN (Electronic)9781557528209
StatePublished - 2022
EventComputational Optical Sensing and Imaging, COSI 2022 - Vancouver, Canada
Duration: Jul 11 2022Jul 15 2022

Publication series

NameOptics InfoBase Conference Papers

Conference

ConferenceComputational Optical Sensing and Imaging, COSI 2022
Country/TerritoryCanada
CityVancouver
Period7/11/227/15/22

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials

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