@inproceedings{7d609e8bfc504f96ac5dd37ff55b1c91,
title = "Detecting lower extremity vascular dynamics in patients with peripheral artery disease using diffuse optical tomography",
abstract = "Peripheral Artery Disease (PAD) affects over 10 million Americans and is associated with significant morbidity and mortality. While in many cases the ankle-brachial index (ABI) can be used for diagnosing the disease, this parameter is not dependable in the diabetic and elderly population. These populations tend to have calcified arteries, which leads to elevated ABI values. Dynamic optical tomography (DDOT) promises to overcome the limitations of the current diagnostic techniques and has the potential to initiate a paradigm shift in the diagnosis of vascular disease. We have performed initial pilot studies involving 5 PAD patients and 3 healthy volunteers. The time traces and tomographic reconstruction obtained from measurements on the feet show significant differences between healthy and affected vasculatures. In addition, we found that DOT is capable of identifying PAD in diabetic patients, who are misdiagnosed by the traditional ABI screening.",
keywords = "Diabetes, Diffuse Optical Tomography, Dynamic Imaging, Vascular Imaging",
author = "Khalil, {Michael A.} and Kim, {Hyun Keol K.} and Kim, {In Kyong} and Rajeev Dayal and Hielscher, {Andreas H.}",
note = "Copyright: Copyright 2011 Elsevier B.V., All rights reserved.; Optical Tomography and Spectroscopy of Tissue IX ; Conference date: 23-01-2011 Through 26-01-2011",
year = "2011",
doi = "10.1117/12.874236",
language = "English (US)",
isbn = "9780819484338",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Optical Tomography and Spectroscopy of Tissue IX",
}