Development of a Brief Parent-Report Screen for Common Gastrointestinal Disorders in Autism Spectrum Disorder

Kara G. Margolis, Timothy M. Buie, J. Blake Turner, Anna E. Silberman, Judith F. Feldman, Katherine F. Murray, Maureen McSwiggan-Hardin, Joseph Levy, Margaret L. Bauman, Jeremy Veenstra-VanderWeele, Agnes H. Whitaker, Harland S. Winter

Research output: Contribution to journalArticlepeer-review

Abstract

Gastrointestinal dysfunction in children with autism spectrum disorder (ASD) is common and associated with problem behaviors. This study describes the development of a brief, parent-report screen that relies minimally upon the child’s ability to report or localize pain for identifying children with ASD at risk for one of three common gastrointestinal disorders (functional constipation, functional diarrhea, and gastroesophageal reflux disease). In a clinical sample of children with ASD, this 17-item screen identified children having one or more of these disorders with a sensitivity of 84%, specificity of 43%, and a positive predictive value of 67%. If found to be valid in an independent sample of children with ASD, the screen will be useful in both clinical practice and research.

Original languageEnglish (US)
Pages (from-to)349-362
Number of pages14
JournalJournal of Autism and Developmental Disorders
Volume49
Issue number1
DOIs
StatePublished - Jan 15 2019

Keywords

  • Autism
  • Behavior
  • Comorbidities
  • Gastrointestinal
  • GI
  • Screen

ASJC Scopus subject areas

  • Developmental and Educational Psychology

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