Abstract
The synthesis of (±)-peduncularine was accomplished using the [3 + 2] annulation of an allylic silane with chlorosulfonyl isocyanate to assemble the bicyclic core of the alkaloid. The stereochemistry of the annulation product was employed to control the installation of the indolylmethyl side chain at C-7 with complete stereoselectivity.
Original language | English (US) |
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Pages (from-to) | 11342-11348 |
Number of pages | 7 |
Journal | Journal of the American Chemical Society |
Volume | 124 |
Issue number | 38 |
DOIs | |
State | Published - Sep 25 2002 |
ASJC Scopus subject areas
- Catalysis
- General Chemistry
- Biochemistry
- Colloid and Surface Chemistry