Different Rates of LINE-1 (L1) Retrotransposon Amplification and Evolution in New World Monkeys

Stéphane Boissinot, Christian Roos, Anthony V. Furano

Research output: Contribution to journalArticlepeer-review

Abstract

LINE-1 (L1) elements constitute the major family of retrotransposons in mammalian genomes. Here we report the first investigation of L1 evolution in New World monkeys (NWM). Two regions of the second open-reading frame were analyzed by two methods in three NWM species, the squirrel monkey (Saimiri sciureus), the tamarin (Saguinus oedipus), and the spider monkey (Ateles paniscus). Since these three species diverged, L1 has amplified in the Saimiri and Saguinus lineages but L1 activity seems to have been strongly reduced in the Ateles lineage. In addition, the active L1 lineage has evolved rapidly in Saimiri and Saguinus, generating species-specific subfamilies. In contrast, we found no evidence for a species-specific subfamily in Ateles, a result consistent with the low L1 activity in this species for the last ∼25 My.

Original languageEnglish (US)
Pages (from-to)122-130
Number of pages9
JournalJournal of Molecular Evolution
Volume58
Issue number1
DOIs
StatePublished - Jan 2004

Keywords

  • LINE-1
  • New World monkeys
  • Non-LTR
  • Primate
  • Retrotransposon

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics

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