Diffuse backscattering Mueller matrix analysis for tissue diagnostics with polarized light

Andreas H. Hielscher; Sebastian Bartel

Diffuse backscattering Mueller matrix analysis for tissue diagnostics with polarized light

Andreas H. Hielscher, Sebastian Bartel

Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We have developed a Monte Carlo algorithm that calculates all sixteen, two-dimensional elements of the diffusing backscattering Mueller Matrix for highly scattering media. Using the Stokes-Mueller formalism and scattering amplitudes calculated with Mie theory, we are able to consider polarization dependent photon propagation in highly scattering media. The numerically computed matrix elements are compared to experimental data obtained from particle suspensions with different particle sizes and fibroblast cell suspensions. The numerical results show good agreement in both azimuthal and radial direction with the experimental data, and suggest that in the fibroblast suspensions subcellular structures with a typical size of 200 to 300 nm dominate the backscattering behavior.

Original language	English (US)
Title of host publication	Optical Biopsy III
Subtitle of host publication	Proceedings of SPIE - The International Society for Optical Engineering
Pages	43-53
Number of pages	11
Volume	3917
State	Published - 2000
Event	Optical Biopsy III - San Jose, CA, USA Duration: Jan 23 2000 → Jan 24 2000

Publication series

Name	Proceedings of SPIE - The International Society for Optical Engineering
Publisher	SPIE
ISSN (Print)	0277-786X

Conference

Conference	Optical Biopsy III
City	San Jose, CA, USA
Period	1/23/00 → 1/24/00

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

Cite this

Diffuse backscattering Mueller matrix analysis for tissue diagnostics with polarized light. / Hielscher, Andreas H.; Bartel, Sebastian.
Optical Biopsy III: Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3917 2000. p. 43-53 (Proceedings of SPIE - The International Society for Optical Engineering).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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title = "Diffuse backscattering Mueller matrix analysis for tissue diagnostics with polarized light",

abstract = "We have developed a Monte Carlo algorithm that calculates all sixteen, two-dimensional elements of the diffusing backscattering Mueller Matrix for highly scattering media. Using the Stokes-Mueller formalism and scattering amplitudes calculated with Mie theory, we are able to consider polarization dependent photon propagation in highly scattering media. The numerically computed matrix elements are compared to experimental data obtained from particle suspensions with different particle sizes and fibroblast cell suspensions. The numerical results show good agreement in both azimuthal and radial direction with the experimental data, and suggest that in the fibroblast suspensions subcellular structures with a typical size of 200 to 300 nm dominate the backscattering behavior.",

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AU - Hielscher, Andreas H.

AU - Bartel, Sebastian

PY - 2000

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N2 - We have developed a Monte Carlo algorithm that calculates all sixteen, two-dimensional elements of the diffusing backscattering Mueller Matrix for highly scattering media. Using the Stokes-Mueller formalism and scattering amplitudes calculated with Mie theory, we are able to consider polarization dependent photon propagation in highly scattering media. The numerically computed matrix elements are compared to experimental data obtained from particle suspensions with different particle sizes and fibroblast cell suspensions. The numerical results show good agreement in both azimuthal and radial direction with the experimental data, and suggest that in the fibroblast suspensions subcellular structures with a typical size of 200 to 300 nm dominate the backscattering behavior.

AB - We have developed a Monte Carlo algorithm that calculates all sixteen, two-dimensional elements of the diffusing backscattering Mueller Matrix for highly scattering media. Using the Stokes-Mueller formalism and scattering amplitudes calculated with Mie theory, we are able to consider polarization dependent photon propagation in highly scattering media. The numerically computed matrix elements are compared to experimental data obtained from particle suspensions with different particle sizes and fibroblast cell suspensions. The numerical results show good agreement in both azimuthal and radial direction with the experimental data, and suggest that in the fibroblast suspensions subcellular structures with a typical size of 200 to 300 nm dominate the backscattering behavior.

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M3 - Conference contribution

AN - SCOPUS:0033719905

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Y2 - 23 January 2000 through 24 January 2000

ER -

Diffuse backscattering Mueller matrix analysis for tissue diagnostics with polarized light

Abstract

Publication series

Conference

ASJC Scopus subject areas

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