Diffuse backscattering Mueller matrix analysis for tissue diagnostics with polarized light

Andreas H. Hielscher, Sebastian Bartel

    Research output: Contribution to journalConference articlepeer-review


    We have developed a Monte Carlo algorithm that calculates all sixteen, two-dimensional elements of the diffusing backscattering Mueller Matrix for highly scattering media. Using the Stokes-Mueller formalism and scattering amplitudes calculated with Mie theory, we are able to consider polarization dependent photon propagation in highly scattering media. The numerically computed matrix elements are compared to experimental data obtained from particle suspensions with different particle sizes and fibroblast cell suspensions. The numerical results show good agreement in both azimuthal and radial direction with the experimental data, and suggest that in the fibroblast suspensions subcellular structures with a typical size of 200 to 300 nm dominate the backscattering behavior.

    Original languageEnglish (US)
    Pages (from-to)43-53
    Number of pages11
    JournalProceedings of SPIE - The International Society for Optical Engineering
    StatePublished - 2000
    EventOptical Biopsy III - San Jose, CA, USA
    Duration: Jan 23 2000Jan 24 2000

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Condensed Matter Physics
    • Computer Science Applications
    • Applied Mathematics
    • Electrical and Electronic Engineering


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