Diffusion tensor imaging of traumatic brain injury review: Implications for neurorehabilitation

Gerald T. Voelbel, Helen M. Genova, Nancy D. Chiaravalotti, Matthew J. Hoptman

Research output: Contribution to journalReview articlepeer-review


Diffusion tensor imaging (DTI) has widely been used to investigate the microstructural damage of white matter tracts that occur in individuals with traumatic brain injury (TBI). In the current review, we discuss the white matter regions which are commonly affected in adults with TBI. We also describe the current literature that has utilized DTI to investigate the relationship between microstructural integrity with neuropsychological performance and clinical outcome measures. Finally, a model is presented of the potential utilization of DTI as a biomarker of efficacy in neurorehabilitation for individuals with TBI.

Original languageEnglish (US)
Pages (from-to)281-293
Number of pages13
Issue number3
StatePublished - 2012


  • diffusion tensor imaging
  • neurorehabilitation
  • Traumatic brain injury
  • TBI
  • brain injury
  • neuroscience

ASJC Scopus subject areas

  • Clinical Neurology
  • Rehabilitation
  • Physical Therapy, Sports Therapy and Rehabilitation


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