Digital detection techniques for dynamic optical tomographic imaging

Joseph M. Lasker, James Masciotti, Mathew Schoenecker, Christoph Schmitz, Andreas Hielscher

Research output: Chapter in Book/Report/Conference proceedingConference contribution


In this paper we present a novel application of digital detection and data-acquisition techniques to a prototype dynamic optical tomography system. The core component is a digital signal processor (DSP) that is responsible for collecting and processing the digitized data set. Utilizing the processing power of the DSP, real-time data rates for this 16-source, 32-detector system, can be achieved at rates as high as 140Hz per tomographic frame. Many of the synchronously-timed processes are controlled by a complex programmable logic device (CPLD) that is used in conjunction with the DSP to orchestrate data flow. The operation of the instrument is managed through a comprehensive graphical user interface, which was designed using the LabVIEW software package. Performance analysis demonstrates very low system noise (∼.60pW RMS noise equivalent power) and excellent signal precision (<0.1%) for most practical cases. First experiments on tissue phantoms show that dynamic behavior can be accurately captured using this system.

Original languageEnglish (US)
Title of host publicationOptical Tomography and Spectroscopy of Tissue VII
StatePublished - 2007
EventOptical Tomography and Spectroscopy of Tissue VII - San Jose, CA, United States
Duration: Jan 21 2007Jan 24 2007

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceOptical Tomography and Spectroscopy of Tissue VII
Country/TerritoryUnited States
CitySan Jose, CA

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging


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