Discrimination is associated with C-reactive protein among young sexual minority men

Stephanie H. Cook, Natalie Slopen, Laura Scarimbolo, Nicholas Mirin, Erica P. Wood, Nicole Rosendale, Rumi Chunara, Colin W. Burke, Perry N. Halkitis

Research output: Contribution to journalArticlepeer-review


This report examines associations between everyday discrimination, microaggressions, and CRP to gain insight on potential mechanisms that may underlie increased CVD risk among sexual minority male young adults. The sample consisted of 60 participants taken from the P18 cohort between the ages of 24 and 28 years. Multinomial logistic regression models were used to examine the association between perceived everyday discrimination and LGBQ microaggressions with C-reactive protein cardiovascular risk categories of low-, average-, and high-risk, as defined by the American Heart Association and Centers for Disease Control. Adjustments were made for BMI. Individuals who experienced more everyday discrimination had a higher risk of being classified in the high-risk CRP group compared to the low-risk CRP group (RRR = 3.35, p = 0.02). Interpersonal LGBQ microaggressions were not associated with CRP risk category. Everyday discrimination, but not specific microaggressions based on sexual orientation, were associated with elevated levels of CRP among young sexual minority men (YSMM). Thus, to implement culturally and age-appropriate interventions, further researcher is needed to critically examine the specific types of discrimination and the resultant impact on YSMM’s health.

Original languageEnglish (US)
Pages (from-to)649-657
Number of pages9
JournalJournal of Behavioral Medicine
Issue number4
StatePublished - Aug 2022


  • C-reactive protein (CRP)
  • Discrimination
  • Microaggressions
  • Sexual minority men

ASJC Scopus subject areas

  • General Psychology
  • Psychiatry and Mental health


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