TY - JOUR
T1 - Disentangling the effects of high permittivity materials on signal optimization and sample noise reduction via ideal current patterns
AU - Vaidya, Manushka V.
AU - Sodickson, Daniel K.
AU - Collins, Christopher M.
AU - Lattanzi, Riccardo
N1 - Funding Information:
Foundation for the National Institutes of Health, Grant/Award Number: NIH P41 EB017183, NIH R01 EB0011551, NIH R01 EB002568, NIH R01 EB021277 and NIH R01 EB024536; National Science Foundation, Grant/Award Number: 1453675
Funding Information:
This work was supported in part by NIH R01 EB002568, NIH R01 EB024536, NIH R01 EB0011551, NIH R01 EB021277, and NSF 1453675, and it was performed under the rubric of the Center for Advanced Imaging Innovation and Research (CAI2R, www.cai2r.net), a NIBIB Biomedical Technology Resource Center (NIH P41 EB017183). The authors would like to thank Giuseppe Carluccio and Jan Paska for insightful discussions and suggestions. This study was supported in part by the National Institutes of Health (NIH) grants R01 EB002568, R01 EB024536, R01 EB0011551, and R01 EB021277; and the National Science Foundation (NSF) 1453675. It was performed under the rubric of the Center for Advanced Imaging Innovation and Research (CAI2R, www.cai2r.net), a National Institute of Biomedical Imaging and Bioengineering (NIBIB) Biomedical Technology Resource Center (NIH P41 EB017183).
Funding Information:
This work was supported in part by NIH R01 EB002568, NIH R01 EB024536, NIH R01 EB0011551, NIH R01 EB021277, and NSF 1453675, and it was performed under the rubric of the Center for Advanced Imaging Innovation and Research (CAI2R, www.cai2r.net), a NIBIB Biomedical Technology
Funding Information:
This study was supported in part by the National Institutes of Health (NIH) grants R01 EB002568, R01 EB024536, R01 EB0011551, and R01 EB021277; and the National Science Foundation (NSF) 1453675. It was performed under the rubric of the Center for Advanced Imaging Innovation and Research (CAI2R, www.cai2r.net), a National Institute of Biomedical Imaging and Bioengineering (NIBIB) Biomedical Technology Resource Center (NIH P41 EB017183).
Publisher Copyright:
© 2018 International Society for Magnetic Resonance in Medicine
PY - 2019/4
Y1 - 2019/4
N2 - Purpose: To investigate how high-permittivity materials (HPMs) can improve SNR when placed between MR detectors and the imaged body. Methods: We used a simulation framework based on dyadic Green’s functions to calculate the electromagnetic field inside a uniform dielectric sphere at 7 Tesla, with and without a surrounding layer of HPM. SNR-optimizing (ideal) current patterns were expressed as the sum of signal-optimizing (signal-only) current patterns and dark mode current patterns that minimize sample noise while contributing nothing to signal. We investigated how HPM affects the shape and amplitude of these current patterns, sample noise, and array SNR. Results: Ideal and signal-only current patterns were identical for a central voxel. HPMs introduced a phase shift into these patterns, compensating for signal propagation delay in the HPMs. For an intermediate location within the sphere, dark mode current patterns were present and illustrated the mechanisms by which HPMs can reduce sample noise. High-amplitude signal-only current patterns were observed for HPM configurations that shield the electromagnetic field from the sample. For coil arrays, these configurations corresponded to poor SNR in deep regions but resulted in large SNR gains near the surface due to enhanced fields in the vicinity of the HPM. For very high relative permittivity values, HPM thicknesses corresponding to even multiples of λ/4 resulted in coil SNR gains throughout the sample. Conclusion: HPMs affect both signal sensitivity and sample noise. Lower amplitude signal-only optimal currents corresponded to higher array SNR performance and could guide the design of coils integrated with HPM.
AB - Purpose: To investigate how high-permittivity materials (HPMs) can improve SNR when placed between MR detectors and the imaged body. Methods: We used a simulation framework based on dyadic Green’s functions to calculate the electromagnetic field inside a uniform dielectric sphere at 7 Tesla, with and without a surrounding layer of HPM. SNR-optimizing (ideal) current patterns were expressed as the sum of signal-optimizing (signal-only) current patterns and dark mode current patterns that minimize sample noise while contributing nothing to signal. We investigated how HPM affects the shape and amplitude of these current patterns, sample noise, and array SNR. Results: Ideal and signal-only current patterns were identical for a central voxel. HPMs introduced a phase shift into these patterns, compensating for signal propagation delay in the HPMs. For an intermediate location within the sphere, dark mode current patterns were present and illustrated the mechanisms by which HPMs can reduce sample noise. High-amplitude signal-only current patterns were observed for HPM configurations that shield the electromagnetic field from the sample. For coil arrays, these configurations corresponded to poor SNR in deep regions but resulted in large SNR gains near the surface due to enhanced fields in the vicinity of the HPM. For very high relative permittivity values, HPM thicknesses corresponding to even multiples of λ/4 resulted in coil SNR gains throughout the sample. Conclusion: HPMs affect both signal sensitivity and sample noise. Lower amplitude signal-only optimal currents corresponded to higher array SNR performance and could guide the design of coils integrated with HPM.
KW - SNR
KW - dyadic Green’s function
KW - high permittivity materials
KW - ideal current patterns
KW - ultimate intrinsic SNR
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U2 - 10.1002/mrm.27554
DO - 10.1002/mrm.27554
M3 - Article
C2 - 30426554
AN - SCOPUS:85056434273
SN - 0740-3194
VL - 81
SP - 2746
EP - 2758
JO - Magnetic Resonance in Medicine
JF - Magnetic Resonance in Medicine
IS - 4
ER -