TY - JOUR
T1 - Disinfection of immature teeth with a triple antibiotic paste
AU - Windley, William
AU - Teixeira, Fabricio
AU - Levin, Linda
AU - Sigurdsson, Asgeir
AU - Trope, Martin
PY - 2005/6
Y1 - 2005/6
N2 - This study assessed the efficacy of a triple antibiotic paste in the disinfection of immature dog teeth with apical periodontitis. The canals were sampled before (S1) and after (S2) irrigation with 1.25% NaOCL and after dressing with a triple antibiotic paste (S3), consisting of metronidazole, ciprofloxacin, and minocycline. At S1, 100% of the samples cultured positive for bacteria with a mean CFU count of 1.7 × 108. At S2, 10% of the samples cultured bacteria-free with a mean CFU count of 1.4 × 10 4. At S3, 70% of the samples cultured bacteria-free with a mean CFU count of only 26. Reductions in mean CFU counts between S1 and S2 (p < 0.0001) as well as between S2 and S3 (p < 0.0001) were statistically significant. These results indicate the effectiveness of a triple antibiotic paste in the disinfection of immature teeth with apical periodontitis.
AB - This study assessed the efficacy of a triple antibiotic paste in the disinfection of immature dog teeth with apical periodontitis. The canals were sampled before (S1) and after (S2) irrigation with 1.25% NaOCL and after dressing with a triple antibiotic paste (S3), consisting of metronidazole, ciprofloxacin, and minocycline. At S1, 100% of the samples cultured positive for bacteria with a mean CFU count of 1.7 × 108. At S2, 10% of the samples cultured bacteria-free with a mean CFU count of 1.4 × 10 4. At S3, 70% of the samples cultured bacteria-free with a mean CFU count of only 26. Reductions in mean CFU counts between S1 and S2 (p < 0.0001) as well as between S2 and S3 (p < 0.0001) were statistically significant. These results indicate the effectiveness of a triple antibiotic paste in the disinfection of immature teeth with apical periodontitis.
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U2 - 10.1097/01.don.0000148143.80283.ea
DO - 10.1097/01.don.0000148143.80283.ea
M3 - Article
C2 - 15917683
AN - SCOPUS:20444435147
SN - 0099-2399
VL - 31
SP - 439
EP - 443
JO - Journal of endodontics
JF - Journal of endodontics
IS - 6
ER -