Disinfection of immature teeth with a triple antibiotic paste

William Windley, Fabricio Teixeira, Linda Levin, Asgeir Sigurdsson, Martin Trope

Research output: Contribution to journalArticle

Abstract

This study assessed the efficacy of a triple antibiotic paste in the disinfection of immature dog teeth with apical periodontitis. The canals were sampled before (S1) and after (S2) irrigation with 1.25% NaOCL and after dressing with a triple antibiotic paste (S3), consisting of metronidazole, ciprofloxacin, and minocycline. At S1, 100% of the samples cultured positive for bacteria with a mean CFU count of 1.7 × 108. At S2, 10% of the samples cultured bacteria-free with a mean CFU count of 1.4 × 10 4. At S3, 70% of the samples cultured bacteria-free with a mean CFU count of only 26. Reductions in mean CFU counts between S1 and S2 (p < 0.0001) as well as between S2 and S3 (p < 0.0001) were statistically significant. These results indicate the effectiveness of a triple antibiotic paste in the disinfection of immature teeth with apical periodontitis.

Original languageEnglish (US)
Pages (from-to)439-443
Number of pages5
JournalJournal of endodontics
Volume31
Issue number6
DOIs
StatePublished - Jun 2005

ASJC Scopus subject areas

  • Dentistry(all)

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