TY - JOUR
T1 - DNA and PNA as templates for building nanoassemblies via electrostatic complexation with gold nanoparticles
AU - Gourishankar, A.
AU - Shukla, S.
AU - Pasricha, R.
AU - Sastry, M.
AU - Ganesh, K. N.
N1 - Funding Information:
A.G. and S.S. thank CSIR, New Delhi for award of fellowships. This work is a part of research grant provided by DST, New Delhi to K.N.G. and M.S. under Nanotechnology Initiative Programme. The work was presented at Indo–Japanese Workshop on Advanced Molecular Electronics and Bionics organized by DST (India) and JSPS (Japan) at Kitakyushu Institute of Technology, Kitakyushu during December 11–12, 2003.
PY - 2005/2
Y1 - 2005/2
N2 - Organisation of nanoparticles on structurally well-defined templates is a first step towards creating nanomachines. In this respect, nucleic acids are ideal structural templates and a variety of secondary structures realizable from DNA/RNA-e.g., duplexes, hairpins, triplexes, cruciforms, tetraplexes can be exploited to engineer nanoparticle organization at will. We have used oligonucleotides and their analogues such as phosphorothioates and peptide nucleic acids to electrostatically encapsulate cationic-capped gold nanoparticles. This article describes synthesis and characterization of DNA/PNA-gold nanoparticle composites using TEM and UV-Tm techniques. These types of assemblies may have potential for creating nanowires and lithographic circuits.
AB - Organisation of nanoparticles on structurally well-defined templates is a first step towards creating nanomachines. In this respect, nucleic acids are ideal structural templates and a variety of secondary structures realizable from DNA/RNA-e.g., duplexes, hairpins, triplexes, cruciforms, tetraplexes can be exploited to engineer nanoparticle organization at will. We have used oligonucleotides and their analogues such as phosphorothioates and peptide nucleic acids to electrostatically encapsulate cationic-capped gold nanoparticles. This article describes synthesis and characterization of DNA/PNA-gold nanoparticle composites using TEM and UV-Tm techniques. These types of assemblies may have potential for creating nanowires and lithographic circuits.
KW - DNA
KW - DNA-gold nanoparticle interactions
KW - Nanoassemblies
KW - PNA
UR - http://www.scopus.com/inward/record.url?scp=10244226724&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=10244226724&partnerID=8YFLogxK
U2 - 10.1016/j.cap.2004.06.020
DO - 10.1016/j.cap.2004.06.020
M3 - Conference article
AN - SCOPUS:10244226724
SN - 1567-1739
VL - 5
SP - 102
EP - 107
JO - Current Applied Physics
JF - Current Applied Physics
IS - 2
T2 - Indo-Japan Workshop on Advanced Molecular Electronics
Y2 - 11 December 2003 through 12 December 2003
ER -