DNA: Beyond the Double Helix

Nadrian C. Seeman

Research output: Contribution to journalArticlepeer-review


Reciprocal exchange can be used to produce DNA motifs based on branching at the level of secondary structure. These motifs can be combined by sticky-ended cohesion to produce a variety of structures. Stick polyhedra and nanomechanical devices have been produced by self-assembly from motifs based on branched DNA. Periodic arrays with tunable surface features has also been produced; aperiodic arrangements have been used for DNA-based computation.

Original languageEnglish (US)
Pages (from-to)237-244
Number of pages8
JournalMacromolecular Symposia
StatePublished - Sep 2003


  • Branched DNA
  • DNA-based computation
  • Periodic arrays
  • Self-assembly
  • Stick polyhedra
  • Surface features
  • Tunable nanomechanical devices

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry


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