DNA cruciforms

Neville R. Kallenbach; Min Zhong

doi:10.1016/S0959-440X(94)90104-X

DNA cruciforms

Neville R. Kallenbach, Min Zhong

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Cruciforms represent a novel DNA state with unique physical and biological properties, including the ability to undergo branch migration in appropriate sequence backgrounds. Recent results establish a preferred geometry of immobile cruciforms in Mg²⁺ solution, the rate of branch migration, and the binding properties of cruciforms for proteins and small molecule ligands. A structure has been determined for three-arm branches with unpaired bases at the branch.

Original language	English (US)
Pages (from-to)	365-371
Number of pages	7
Journal	Current Opinion in Structural Biology
Volume	4
Issue number	3
DOIs	https://doi.org/10.1016/S0959-440X(94)90104-X
State	Published - Jun 1994

ASJC Scopus subject areas

Structural Biology
Molecular Biology

Access to Document

10.1016/S0959-440X(94)90104-X

Fingerprint Dive into the research topics of 'DNA cruciforms'. Together they form a unique fingerprint.

Cite this

@article{f4b7949a65844d349ce45bed761b51e4,

title = "DNA cruciforms",

abstract = "Cruciforms represent a novel DNA state with unique physical and biological properties, including the ability to undergo branch migration in appropriate sequence backgrounds. Recent results establish a preferred geometry of immobile cruciforms in Mg2+ solution, the rate of branch migration, and the binding properties of cruciforms for proteins and small molecule ligands. A structure has been determined for three-arm branches with unpaired bases at the branch.",

author = "Kallenbach, {Neville R.} and Min Zhong",

note = "Funding Information: We thank our colleagues for providing reprints and preprints of articles and for helpful discussions. Work from the authors' laboratory is suplx~rted by National Institutes of Health grant CA24101. Copyright: Copyright 2015 Elsevier B.V., All rights reserved.",

year = "1994",

month = jun,

doi = "10.1016/S0959-440X(94)90104-X",

language = "English (US)",

volume = "4",

pages = "365--371",

journal = "Current Opinion in Structural Biology",

issn = "0959-440X",

publisher = "Elsevier Limited",

number = "3",

}

TY - JOUR

T1 - DNA cruciforms

AU - Kallenbach, Neville R.

AU - Zhong, Min

N1 - Funding Information: We thank our colleagues for providing reprints and preprints of articles and for helpful discussions. Work from the authors' laboratory is suplx~rted by National Institutes of Health grant CA24101. Copyright: Copyright 2015 Elsevier B.V., All rights reserved.

PY - 1994/6

Y1 - 1994/6

N2 - Cruciforms represent a novel DNA state with unique physical and biological properties, including the ability to undergo branch migration in appropriate sequence backgrounds. Recent results establish a preferred geometry of immobile cruciforms in Mg2+ solution, the rate of branch migration, and the binding properties of cruciforms for proteins and small molecule ligands. A structure has been determined for three-arm branches with unpaired bases at the branch.

AB - Cruciforms represent a novel DNA state with unique physical and biological properties, including the ability to undergo branch migration in appropriate sequence backgrounds. Recent results establish a preferred geometry of immobile cruciforms in Mg2+ solution, the rate of branch migration, and the binding properties of cruciforms for proteins and small molecule ligands. A structure has been determined for three-arm branches with unpaired bases at the branch.

UR - http://www.scopus.com/inward/record.url?scp=0028233233&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028233233&partnerID=8YFLogxK

U2 - 10.1016/S0959-440X(94)90104-X

DO - 10.1016/S0959-440X(94)90104-X

M3 - Article

AN - SCOPUS:0028233233

VL - 4

SP - 365

EP - 371

JO - Current Opinion in Structural Biology

JF - Current Opinion in Structural Biology

SN - 0959-440X

IS - 3

ER -

DNA cruciforms

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this