DNA engineering and its application to nanotechnology

Nadrian C. Seeman

doi:10.1016/S0167-7799(99)01360-8

DNA engineering and its application to nanotechnology

Nadrian C. Seeman

Chemistry

Research output: Contribution to journal › Review article › peer-review

Abstract

The combination of branched DNA molecules and 'sticky' ends creates a powerful molecular assembly kit for structural DNA nanotechnology. Polyhedra, complex topological objects, a nanomechanical device and two-dimensional arrays with programmable surface features have already been produced in this way. Future applications range from macromolecular crystallography and new materials to molecular electronics and DNA-based computation. Copyright (C) 1999 Elsevier Science Ltd.

Original language	English (US)
Pages (from-to)	437-443
Number of pages	7
Journal	Trends in Biotechnology
Volume	17
Issue number	11
DOIs	https://doi.org/10.1016/S0167-7799(99)01360-8
State	Published - Nov 1 1999

ASJC Scopus subject areas

Biotechnology
Bioengineering

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10.1016/S0167-7799(99)01360-8

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title = "DNA engineering and its application to nanotechnology",

abstract = "The combination of branched DNA molecules and 'sticky' ends creates a powerful molecular assembly kit for structural DNA nanotechnology. Polyhedra, complex topological objects, a nanomechanical device and two-dimensional arrays with programmable surface features have already been produced in this way. Future applications range from macromolecular crystallography and new materials to molecular electronics and DNA-based computation. Copyright (C) 1999 Elsevier Science Ltd.",

author = "Seeman, {Nadrian C.}",

note = "Funding Information: The author{\textquoteright}s work has been supported by the US National Institute of General Medical Sciences (grant GM-29554), the US Office of Naval Research (grant N00014-98-I-0093), DARPA/National Science Foundation (grant NSF-CCR-97-25021) and the Information Directorate of the Rome NY Air Force Research Laboratory (F30602-98-C-0148).",

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N2 - The combination of branched DNA molecules and 'sticky' ends creates a powerful molecular assembly kit for structural DNA nanotechnology. Polyhedra, complex topological objects, a nanomechanical device and two-dimensional arrays with programmable surface features have already been produced in this way. Future applications range from macromolecular crystallography and new materials to molecular electronics and DNA-based computation. Copyright (C) 1999 Elsevier Science Ltd.

AB - The combination of branched DNA molecules and 'sticky' ends creates a powerful molecular assembly kit for structural DNA nanotechnology. Polyhedra, complex topological objects, a nanomechanical device and two-dimensional arrays with programmable surface features have already been produced in this way. Future applications range from macromolecular crystallography and new materials to molecular electronics and DNA-based computation. Copyright (C) 1999 Elsevier Science Ltd.

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DNA engineering and its application to nanotechnology

Abstract

ASJC Scopus subject areas

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