Immobile DNA branched junctions are a complex macromolecular system whose structural features are readily tractable to a simple sequence-design algorithm based on the minimization of sequence symmetry. This algorithm has been applied to the construction of Holliday recombination analogs and to multiply-connected geometrical objects, including a DNA molecule with the connectivity of a cube.
|Original language||English (US)|
|Number of pages||9|
|Journal||Current Opinion in Structural Biology|
|State||Published - Aug 1991|
ASJC Scopus subject areas
- Structural Biology
- Molecular Biology