Does experimentally-induced amblyopia cause hyperopia in monkeys?

Lynne Kiorpes, Josh Wallman

Research output: Contribution to journalArticlepeer-review


We assessed refractive errors in 19 monkeys (Macaca nemestrina) raised with experimentally produced strabismus or unilateral defocus. These procedures resulted in hyperopic anisometropia in 10 monkeys. All 10 of the hyperopic animals were amblyopic; the amblyopic eye was always the more hyperopic eye. The degree of anisometropia was correlated with the degree of amblyopia. Hyperopic anisometropia did not develop in non-amblyopic animals. There was an association between early onset of visual abnormality and later development of hyperopic anisometropia. Since the refractive changes were correlated with changes in axial length and vitreous chamber depth, we suggest that amblyopia may cause alterations in eye growth and late-onset hyperopia.

Original languageEnglish (US)
Pages (from-to)1289-1297
Number of pages9
JournalVision research
Issue number9
StatePublished - May 1995


  • Amblyopia
  • Defocus
  • Hyperopia
  • Monkey
  • Strabismus

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems


Dive into the research topics of 'Does experimentally-induced amblyopia cause hyperopia in monkeys?'. Together they form a unique fingerprint.

Cite this