Dynamic contact-free continuous-wave diffuse optical tomography system for the detection of vascular dynamics within the foot

M. A. Khalil; J. Hoi; H. K. Kim; A. H. Hielscher

doi:10.1117/12.2003424

Dynamic contact-free continuous-wave diffuse optical tomography system for the detection of vascular dynamics within the foot

M. A. Khalil, J. Hoi, H. K. Kim, A. H. Hielscher

Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We present a dynamic contact-free continuous-wave diffuse optical tomography system for the detection and monitoring of peripheral arterial disease (PAD) in the foot. Peripheral Arterial Disease (PAD) is the narrowing of the functional area of the artery generally due to atherosclerosis. It affects between 8-12 million people in the United States and if untreated this can lead to ulceration, gangrene and ultimately amputation. Contact-Free imaging is highly desirable, due to the presence of ulcerations and gangrene in many patients affected by PAD. The system uses an electron multiplying charge coupled device (EMCCD) camera for detection to achieve a dynamic range of 86 dB with a frame rate of 1 Hz using 20 collimated source fibers and 2 wavelengths. We present first clinical results showing 3D images of total hemoglobin changes in response to a dynamic thigh cuff.

Original language	English (US)
Title of host publication	Optical Tomography and Spectroscopy of Tissue X
DOIs	https://doi.org/10.1117/12.2003424
State	Published - 2013
Event	Optical Tomography and Spectroscopy of Tissue X - San Francisco, CA, United States Duration: Feb 3 2013 → Feb 6 2013

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	8578
ISSN (Print)	1605-7422

Conference

Conference	Optical Tomography and Spectroscopy of Tissue X
Country/Territory	United States
City	San Francisco, CA
Period	2/3/13 → 2/6/13

Keywords

Peripheral arterial disease
diffuse optical tomography
dynamic imaging
vascular dynamics

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Radiology Nuclear Medicine and imaging
Biomaterials

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10.1117/12.2003424

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Dynamic contact-free continuous-wave diffuse optical tomography system for the detection of vascular dynamics within the foot. / Khalil, M. A.; Hoi, J.; Kim, H. K. et al.
Optical Tomography and Spectroscopy of Tissue X. 2013. 85781H (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8578).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Khalil, MA, Hoi, J, Kim, HK & Hielscher, AH 2013, Dynamic contact-free continuous-wave diffuse optical tomography system for the detection of vascular dynamics within the foot. in Optical Tomography and Spectroscopy of Tissue X., 85781H, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 8578, Optical Tomography and Spectroscopy of Tissue X, San Francisco, CA, United States, 2/3/13. https://doi.org/10.1117/12.2003424

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title = "Dynamic contact-free continuous-wave diffuse optical tomography system for the detection of vascular dynamics within the foot",

abstract = "We present a dynamic contact-free continuous-wave diffuse optical tomography system for the detection and monitoring of peripheral arterial disease (PAD) in the foot. Peripheral Arterial Disease (PAD) is the narrowing of the functional area of the artery generally due to atherosclerosis. It affects between 8-12 million people in the United States and if untreated this can lead to ulceration, gangrene and ultimately amputation. Contact-Free imaging is highly desirable, due to the presence of ulcerations and gangrene in many patients affected by PAD. The system uses an electron multiplying charge coupled device (EMCCD) camera for detection to achieve a dynamic range of 86 dB with a frame rate of 1 Hz using 20 collimated source fibers and 2 wavelengths. We present first clinical results showing 3D images of total hemoglobin changes in response to a dynamic thigh cuff.",

keywords = "Peripheral arterial disease, diffuse optical tomography, dynamic imaging, vascular dynamics",

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AU - Hoi, J.

AU - Kim, H. K.

AU - Hielscher, A. H.

PY - 2013

Y1 - 2013

N2 - We present a dynamic contact-free continuous-wave diffuse optical tomography system for the detection and monitoring of peripheral arterial disease (PAD) in the foot. Peripheral Arterial Disease (PAD) is the narrowing of the functional area of the artery generally due to atherosclerosis. It affects between 8-12 million people in the United States and if untreated this can lead to ulceration, gangrene and ultimately amputation. Contact-Free imaging is highly desirable, due to the presence of ulcerations and gangrene in many patients affected by PAD. The system uses an electron multiplying charge coupled device (EMCCD) camera for detection to achieve a dynamic range of 86 dB with a frame rate of 1 Hz using 20 collimated source fibers and 2 wavelengths. We present first clinical results showing 3D images of total hemoglobin changes in response to a dynamic thigh cuff.

AB - We present a dynamic contact-free continuous-wave diffuse optical tomography system for the detection and monitoring of peripheral arterial disease (PAD) in the foot. Peripheral Arterial Disease (PAD) is the narrowing of the functional area of the artery generally due to atherosclerosis. It affects between 8-12 million people in the United States and if untreated this can lead to ulceration, gangrene and ultimately amputation. Contact-Free imaging is highly desirable, due to the presence of ulcerations and gangrene in many patients affected by PAD. The system uses an electron multiplying charge coupled device (EMCCD) camera for detection to achieve a dynamic range of 86 dB with a frame rate of 1 Hz using 20 collimated source fibers and 2 wavelengths. We present first clinical results showing 3D images of total hemoglobin changes in response to a dynamic thigh cuff.

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KW - diffuse optical tomography

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KW - vascular dynamics

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Dynamic contact-free continuous-wave diffuse optical tomography system for the detection of vascular dynamics within the foot

Abstract

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Conference

Keywords

ASJC Scopus subject areas

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