Dynamic contact-free continuous-wave diffuse optical tomography system for the detection of vascular dynamics within the foot

M. A. Khalil, J. Hoi, H. K. Kim, A. H. Hielscher

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    We present a dynamic contact-free continuous-wave diffuse optical tomography system for the detection and monitoring of peripheral arterial disease (PAD) in the foot. Peripheral Arterial Disease (PAD) is the narrowing of the functional area of the artery generally due to atherosclerosis. It affects between 8-12 million people in the United States and if untreated this can lead to ulceration, gangrene and ultimately amputation. Contact-Free imaging is highly desirable, due to the presence of ulcerations and gangrene in many patients affected by PAD. The system uses an electron multiplying charge coupled device (EMCCD) camera for detection to achieve a dynamic range of 86 dB with a frame rate of 1 Hz using 20 collimated source fibers and 2 wavelengths. We present first clinical results showing 3D images of total hemoglobin changes in response to a dynamic thigh cuff.

    Original languageEnglish (US)
    Title of host publicationOptical Tomography and Spectroscopy of Tissue X
    DOIs
    StatePublished - 2013
    EventOptical Tomography and Spectroscopy of Tissue X - San Francisco, CA, United States
    Duration: Feb 3 2013Feb 6 2013

    Publication series

    NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
    Volume8578
    ISSN (Print)1605-7422

    Conference

    ConferenceOptical Tomography and Spectroscopy of Tissue X
    CountryUnited States
    CitySan Francisco, CA
    Period2/3/132/6/13

    Keywords

    • diffuse optical tomography
    • dynamic imaging
    • Peripheral arterial disease
    • vascular dynamics

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Biomaterials
    • Atomic and Molecular Physics, and Optics
    • Radiology Nuclear Medicine and imaging

    Fingerprint Dive into the research topics of 'Dynamic contact-free continuous-wave diffuse optical tomography system for the detection of vascular dynamics within the foot'. Together they form a unique fingerprint.

    Cite this