Dynamic contact-free continuous-wave diffuse optical tomography system for the detection of vascular dynamics within the foot

M. A. Khalil, J. Hoi, H. K. Kim, A. H. Hielscher

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We present a dynamic contact-free continuous-wave diffuse optical tomography system for the detection and monitoring of peripheral arterial disease (PAD) in the foot. Peripheral Arterial Disease (PAD) is the narrowing of the functional area of the artery generally due to atherosclerosis. It affects between 8-12 million people in the United States and if untreated this can lead to ulceration, gangrene and ultimately amputation. Contact-Free imaging is highly desirable, due to the presence of ulcerations and gangrene in many patients affected by PAD. The system uses an electron multiplying charge coupled device (EMCCD) camera for detection to achieve a dynamic range of 86 dB with a frame rate of 1 Hz using 20 collimated source fibers and 2 wavelengths. We present first clinical results showing 3D images of total hemoglobin changes in response to a dynamic thigh cuff.

Original languageEnglish (US)
Title of host publicationOptical Tomography and Spectroscopy of Tissue X
DOIs
StatePublished - 2013
EventOptical Tomography and Spectroscopy of Tissue X - San Francisco, CA, United States
Duration: Feb 3 2013Feb 6 2013

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8578
ISSN (Print)1605-7422

Conference

ConferenceOptical Tomography and Spectroscopy of Tissue X
Country/TerritoryUnited States
CitySan Francisco, CA
Period2/3/132/6/13

Keywords

  • diffuse optical tomography
  • dynamic imaging
  • Peripheral arterial disease
  • vascular dynamics

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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