Dynamics of orientation selectivity in the primary visual cortex and the importance of cortical inhibition

Robert Shapley, Michael Hawken, Dario L. Ringach

Research output: Contribution to journalReview article

Abstract

To test theories of orientation selectivity in primary visual cortex (V1), we have done experiments to measure the dynamics of orientation tuning of single neurons in the V1 cortex of macaque monkeys. Based on our dynamics results, we propose that a V1 cell's orientation selectivity is generated mainly by both tuned enhancement and global suppression. Enhancement near the preferred orientation is probably caused by feed-forward input from LGN (plus amplification by cortical-cortical interaction). Global suppression could be supplied by cortical inhibition. Additionally, in about 1/3 of V1 neurons (usually the most sharply tuned) there is tuned suppression, centered near the cell's preferred orientation but broader than tuned enhancement. These mechanisms also can explain important features of steady-state selectivity in the V1 neuron population. Furthermore, similar neuronal mechanisms may be used generally throughout the cerebral cortex.

Original languageEnglish (US)
Pages (from-to)689-699
Number of pages11
JournalNeuron
Volume38
Issue number5
DOIs
StatePublished - Jun 5 2003

ASJC Scopus subject areas

  • Neuroscience(all)

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