Effects of Nurse-Delivered Cognitive Behavioral Intervention on Depression and Anxiety for Persons Living With HIV in China: A Clinical Controlled Trial

Shuyu Han, Yan Hu, Michael V. Relf, Marta I. Mulawa, Hongzhou Lu, Lin Zhang, Zheng Zhu, Jianfeng Luo, Yaolin Pei, Bei Wu

Research output: Contribution to journalArticlepeer-review

Abstract

ABSTRACT: Depression and anxiety, which may influence antiretroviral therapy (ART) medication adherence, are prevalent among persons living with HIV (PLWH) in China. This parallel two-arm clinical controlled trial aimed to examine the effects of a nurse-delivered cognitive behavioral intervention (CBI) on depression, anxiety, and ART medication adherence in Chinese PLWH. Using in-person and online recruitment, 140 PLWH ages 18 years and older who were undergoing ART and had a Patient Health Questionnaire-4 score of ≥2 were assigned to the 10-week-long CBI group or the routine follow-up group according to their preference. Outcomes were measured at baseline, postintervention, and 6-month follow-up. Results showed significant intervention effects on depression maintained until the 6-month follow-up. Although anxiety and ART medication adherence did not show robust effects between conditions, amelioration trends for these outcomes were also found. Our study demonstrated that the nurse-delivered CBI could help Chinese PLWH ameliorate depression.

Original languageEnglish (US)
Pages (from-to)79-93
Number of pages15
JournalThe Journal of the Association of Nurses in AIDS Care : JANAC
Volume32
Issue number1
DOIs
StatePublished - Jan 1 2021

ASJC Scopus subject areas

  • Advanced and Specialized Nursing

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