TY - JOUR
T1 - Effects of Nurse-Delivered Cognitive Behavioral Intervention on Depression and Anxiety for Persons Living With HIV in China
T2 - A Clinical Controlled Trial
AU - Han, Shuyu
AU - Hu, Yan
AU - Relf, Michael V.
AU - Mulawa, Marta I.
AU - Lu, Hongzhou
AU - Zhang, Lin
AU - Zhu, Zheng
AU - Luo, Jianfeng
AU - Pei, Yaolin
AU - Wu, Bei
N1 - Publisher Copyright:
Copyright © 2020 Association of Nurses in AIDS Care.
PY - 2021/2/1
Y1 - 2021/2/1
N2 - Depression and anxiety, which may influence antiretroviral therapy (ART) medication adherence, are prevalent among persons living with HIV (PLWH) in China. This parallel two-arm clinical controlled trial aimed to examine the effects of a nurse-delivered cognitive behavioral intervention (CBI) on depression, anxiety, and ART medication adherence in Chinese PLWH. Using in-person and online recruitment, 140 PLWH ages 18 years and older who were undergoing ART and had a Patient Health Questionnaire-4 score of ≥2 were assigned to the 10-week-long CBI group or the routine follow-up group according to their preference. Outcomes were measured at baseline, postintervention, and 6-month follow-up. Results showed significant intervention effects on depression maintained until the 6-month follow-up. Although anxiety and ART medication adherence did not show robust effects between conditions, amelioration trends for these outcomes were also found. Our study demonstrated that the nurse-delivered CBI could help Chinese PLWH ameliorate depression.
AB - Depression and anxiety, which may influence antiretroviral therapy (ART) medication adherence, are prevalent among persons living with HIV (PLWH) in China. This parallel two-arm clinical controlled trial aimed to examine the effects of a nurse-delivered cognitive behavioral intervention (CBI) on depression, anxiety, and ART medication adherence in Chinese PLWH. Using in-person and online recruitment, 140 PLWH ages 18 years and older who were undergoing ART and had a Patient Health Questionnaire-4 score of ≥2 were assigned to the 10-week-long CBI group or the routine follow-up group according to their preference. Outcomes were measured at baseline, postintervention, and 6-month follow-up. Results showed significant intervention effects on depression maintained until the 6-month follow-up. Although anxiety and ART medication adherence did not show robust effects between conditions, amelioration trends for these outcomes were also found. Our study demonstrated that the nurse-delivered CBI could help Chinese PLWH ameliorate depression.
KW - HIV
KW - anxiety
KW - cognitive behavioral therapy
KW - depression
KW - medication adherence
UR - http://www.scopus.com/inward/record.url?scp=85098838084&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85098838084&partnerID=8YFLogxK
U2 - 10.1097/JNC.0000000000000213
DO - 10.1097/JNC.0000000000000213
M3 - Article
C2 - 33177434
AN - SCOPUS:85098838084
SN - 1055-3290
VL - 32
SP - 79
EP - 93
JO - Journal of the Association of Nurses in AIDS Care
JF - Journal of the Association of Nurses in AIDS Care
IS - 1
ER -