TY - JOUR
T1 - Effects of ZDV-based patient education on intentions toward ZDV use, HIV testing and reproduction among a US cohort of women
AU - Healton, Cheryl
AU - Taylor, S.
AU - Messeri, P.
AU - Weinberg, G.
AU - Bamji, M.
N1 - Funding Information:
A multi-site randomized ® eld trial was conducted in nine cities to evaluate a patient education brochure Pregnancy and HIV is AZT the right choice for you and your baby (Department of Health and Human Services, 1995). The brochure was written in 1995, well before the advent of antiretroviral combination therapy, under the auspices of a 26-member provider consortium with federal sponsorship from the Agency for Health Care Policy and Research and the Health Resources and Services Administration. The brochure summarized the ACTG076 protocol and its results and gave a balanced presentation of the pros and cons of taking ZDV following the 076 regimen. The brochure com prised nine pages and was written at a sixth-grade reading level in English, Spanish and French Creole. All subjects elected to read the brochure, although a cassette tape version was available.
Funding Information:
This research was supported by the Maternal and Child Health Bureau, Health Resources and Services Administration, under grant MCHP02027 to the Northern M anhattan Women and Children HIV Project. The authors wish to thank the many Project Directors and Coordinators of the 18 study sites for their co-operation in the study’ s implementation and the 23 members of the New York City Provider Consortium for their efforts in the study’ s design. We also wish to thank M artina Lynch for study implementation and administrative efforts.
PY - 1999
Y1 - 1999
N2 - This study examined the immediate effects of exposure to a patient education brochure concerning the risks and benefits of zidovudine (ZDV) therapy during pregnancy to reduce perinatal HIV transmission (protocol ACTG 076) on related knowledge, behavioural intentions and attitudes of women with and at-risk for HIV-infection. Self-reports were collected from 653 women of childbearing age from community family planning clinics and hospital-based HIV centres in 19 sites from nine US cities between May and November 1995. The intervention was a nine-page patient education brochure in Spanish, Creole and English versions, evenly presenting the pros and cons of ZDV therapy to reduce perinatal HIV-transmission. Brochure exposure increased knowledge (P < 0.001) for all but one scale concerning ZDV resistance and increased the likelihood of women reporting intentions to take ZDV during pregnancy (p < 0.001) and to believe ZDV reduced transmission (p < 0.001). Brochure exposure had differential effects for some subpopulations. Intentions to have or terminate current or future pregnancies, knowledge about ZDV and attitudes toward ZDV varied mostly by ethnicity/race, language preference and HIV status. Pregnancy status, age, education and having an HIV-positive child had less impact on the brochure's effect, while income had no impact.
AB - This study examined the immediate effects of exposure to a patient education brochure concerning the risks and benefits of zidovudine (ZDV) therapy during pregnancy to reduce perinatal HIV transmission (protocol ACTG 076) on related knowledge, behavioural intentions and attitudes of women with and at-risk for HIV-infection. Self-reports were collected from 653 women of childbearing age from community family planning clinics and hospital-based HIV centres in 19 sites from nine US cities between May and November 1995. The intervention was a nine-page patient education brochure in Spanish, Creole and English versions, evenly presenting the pros and cons of ZDV therapy to reduce perinatal HIV-transmission. Brochure exposure increased knowledge (P < 0.001) for all but one scale concerning ZDV resistance and increased the likelihood of women reporting intentions to take ZDV during pregnancy (p < 0.001) and to believe ZDV reduced transmission (p < 0.001). Brochure exposure had differential effects for some subpopulations. Intentions to have or terminate current or future pregnancies, knowledge about ZDV and attitudes toward ZDV varied mostly by ethnicity/race, language preference and HIV status. Pregnancy status, age, education and having an HIV-positive child had less impact on the brochure's effect, while income had no impact.
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U2 - 10.1080/09540129947587
DO - 10.1080/09540129947587
M3 - Article
C2 - 10716008
AN - SCOPUS:0033428675
SN - 0954-0121
VL - 11
SP - 675
EP - 686
JO - AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV
JF - AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV
IS - 6
ER -