@article{c774ebe201344096b02de1d4a69afbe9,
title = "Electrodeformation of White Blood Cells Enriched with Gold Nanoparticles",
abstract = "The elasticity of white blood cells (WBCs) provides valuable insight into the condition of the cells themselves, the presence of some diseases, as well as immune system activity. In this work, we describe a novel process of refined control of WBCs{\textquoteright} elasticity through a combined use of gold nanoparticles (AuNPs) and the microelectrode array device. The capture and controlled deformation of gold nanoparticles enriched white blood cells in vitro are demonstrated and quantified. Gold nanoparticles enhance the effect of electrically induced deformation and make the DEP-related processes more controllable.",
keywords = "Electrodeformation, Lab-on-chip, Leukocytes, Nanoparticles, Young{\textquoteright}s modulus",
author = "Hallfors, {Nicholas G.} and Teo, {Jeremy C.M.} and Bertone, {Peter M.} and Joshi, {Chakra P.} and Ajymurat Orozaliev and Martin, {Matthew N.} and Isakovic, {A. F.}",
note = "Funding Information: Acknowledgments: The authors thank KU BME Dept. for the use of equipment, KU—MASDAR Institute for the access to Microfabrication Facility, and NYU-Abu Dhabi for the assistance in mask making. We express our gratitude to B. Samara and L. George (KU) for technical assistance. We are especially thankful to our colleagues at Brookhaven National Lab for the access to X-ray fluorescence setup and for providing additional cells and chemicals. BNL-CFN and BNL-NSLS-II are funded by the US Department of Energy. NGH acknowledges Graduate Scholarship Fund and HEIC at KU. J.T., M.N.M. and A.F.I. acknowledge KU Internal Research Funds. A.F.I. acknowledges hospitality and support at Cornell CNF, supported by US NSF. Funding Information: The research was funded internally at KUST through KUST Internal Research funds. The authors thank KU BME Dept. for the use of equipment, KU?MASDAR Institute for the access to Microfabrication Facility, and NYU-Abu Dhabi for the assistance in mask making. We express our gratitude to B. Samara and L. George (KU) for technical assistance. We are especially thankful to our colleagues at Brookhaven National Lab for the access to X-ray fluorescence setup and for providing additional cells and chemicals. BNL-CFN and BNL-NSLS-II are funded by the US Department of Energy. NGH acknowledges Graduate Scholarship Fund and HEIC at KU. J.T., M.N.M. and A.F.I. acknowledge KU Internal Research Funds. A.F.I. acknowledges hospitality and support at Cornell CNF, supported by US NSF. Funding Information: Funding: The research was funded internally at KUST through KUST Internal Research funds. Publisher Copyright: {\textcopyright} 2022 by the authors. Licensee MDPI, Basel, Switzerland.",
year = "2022",
month = jan,
doi = "10.3390/pr10010134",
language = "English (US)",
volume = "10",
journal = "Processes",
issn = "2227-9717",
publisher = "MDPI AG",
number = "1",
}