Electrophoresis of a DNA coil near a nanopore

Payam Rowghanian, Alexander Y. Grosberg

    Research output: Contribution to journalArticle

    Abstract

    Motivated by DNA electrophoresis near a nanopore, we consider the flow field around an "elongated jet," a long thin source which injects momentum into a liquid. This solution qualitatively describes the electro-osmotic flow around a long rigid polymer, where due to electrohydrodynamic coupling, the solvent receives momentum from the electric field. Based on the qualitative behavior of the elongated jet solution, we develop a coarse-grained scheme which reproduces the known theoretical results regarding the electrophoretic behavior of a long rigid polymer and a polymer coil in a uniform field, which we then exploit to analyze the electrophoresis of a polymer coil in the nonuniform field near a nanopore.

    Original languageEnglish (US)
    Article number042723
    JournalPhysical Review E - Statistical, Nonlinear, and Soft Matter Physics
    Volume87
    Issue number4
    DOIs
    StatePublished - Apr 29 2013

    ASJC Scopus subject areas

    • Statistical and Nonlinear Physics
    • Statistics and Probability
    • Condensed Matter Physics

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