Electrospun copper oxide nanoparticles as an efficient heterogeneous catalyst for N-arylation of indole

Abdullah Khalil, Aziz Fihri, Mustapha Jouiad, Raed Hashaikeh

Research output: Contribution to journalArticle

Abstract

The N-arylation of indoles with a variety of aryl bromides is reported using copper oxide nanoparticles as a heterogeneous catalyst. These copper oxide nanoparticles, which were produced in a novel, facile, and scalable fashion via an electrospinning technique, resulted in an excellent product yield under mild conditions. Moreover, the catalyst was easily recovered and reused several times without significant loss of activity.

Original languageEnglish (US)
Pages (from-to)5973-5975
Number of pages3
JournalTetrahedron Letters
Volume55
Issue number43
DOIs
StatePublished - Oct 22 2014

Keywords

  • Copper oxide nanoparticles
  • Electrospinning
  • N-arylation
  • Reusable catalyst
  • Scalable catalyst

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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