Abstract
The N-arylation of indoles with a variety of aryl bromides is reported using copper oxide nanoparticles as a heterogeneous catalyst. These copper oxide nanoparticles, which were produced in a novel, facile, and scalable fashion via an electrospinning technique, resulted in an excellent product yield under mild conditions. Moreover, the catalyst was easily recovered and reused several times without significant loss of activity.
Original language | English (US) |
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Pages (from-to) | 5973-5975 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 55 |
Issue number | 43 |
DOIs | |
State | Published - Oct 22 2014 |
Keywords
- Copper oxide nanoparticles
- Electrospinning
- N-arylation
- Reusable catalyst
- Scalable catalyst
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry