TY - JOUR
T1 - Elemental composition of primary lamellar bone differs between parous and nulliparous rhesus macaque females
AU - Cerrito, Paola
AU - Hu, Bin
AU - Goldstein, Justin Z.
AU - Kalisher, Rachel
AU - Bailey, Shara
AU - Bromage, Timothy G.
N1 - Funding Information:
Support was provided by the NSF DDRIG (grant number: 2018357); by the Program in Early Cultures at Brown University; by the 2010 Max Planck Research Award to TGB in respect of the Hard Tissue Research Program in Human Paleobiomics. The Zeiss Gemini 300 FE-SEM was provided by the NIH S10 Shared Instrumentation Program (grant number: 1S10OD026989-01). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. We thank Hosanna Schroeder of Bruker for guidance in data collection.
Publisher Copyright:
© 2022 Cerrito et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
PY - 2022/11
Y1 - 2022/11
N2 - Extracting life history information from mineralized hard tissues of extant and extinct species is an ongoing challenge in evolutionary and conservation studies. Primary lamellar bone is a mineralized tissue with multidien periodicity that begins deposition prenatally and continues until adulthood albeit with concurrent resorption, thus maintaining a record spanning several years of an individual’s life. Here, we use field-emission scanning electron microscopy and energy-dispersive X-ray analysis to measure the relative concentrations of calcium, phosphorous, oxygen, magnesium and sodium in the femora of seven rhesus macaque with known medical and life-history information. We find that the concentration of these elements distinguishes parous from nulliparous females; that in females calcium and phosphorus are lower in bone formed during reproductive events; and that significant differences in relative magnesium concentration correlate with breastfeeding in infants.
AB - Extracting life history information from mineralized hard tissues of extant and extinct species is an ongoing challenge in evolutionary and conservation studies. Primary lamellar bone is a mineralized tissue with multidien periodicity that begins deposition prenatally and continues until adulthood albeit with concurrent resorption, thus maintaining a record spanning several years of an individual’s life. Here, we use field-emission scanning electron microscopy and energy-dispersive X-ray analysis to measure the relative concentrations of calcium, phosphorous, oxygen, magnesium and sodium in the femora of seven rhesus macaque with known medical and life-history information. We find that the concentration of these elements distinguishes parous from nulliparous females; that in females calcium and phosphorus are lower in bone formed during reproductive events; and that significant differences in relative magnesium concentration correlate with breastfeeding in infants.
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U2 - 10.1371/journal.pone.0276866
DO - 10.1371/journal.pone.0276866
M3 - Article
C2 - 36318529
AN - SCOPUS:85141828649
SN - 1932-6203
VL - 17
JO - PLoS One
JF - PLoS One
IS - 11 November
M1 - e0276866
ER -