Empowering the biomedical research community: Innovative SAS deployment on the All of Us Researcher Workbench

Izabelle Humes; Cathy Shyr; Moira Dillon; Zhongjie Liu; Jennifer Peterson; Chris St Jeor; Jacqueline Malkes; Hiral Master; Brandy Mapes; Romuladus Azuine; Nakia Mack; Bassent Abdelbary; Joyonna Gamble-George; Emily Goldmann; Stephanie Cook; Fatemeh Choupani; Rubin Baskir; Sydney McMaster; Chris Lunt; Karriem Watson; Minnkyong Lee; Sophie Schwartz; Ruchi Munshi; David Glazer; Eric Banks; Anthony Philippakis; Melissa Basford; Dan Roden; Paul A. Harris

doi:10.1093/jamia/ocae216

Empowering the biomedical research community: Innovative SAS deployment on the All of Us Researcher Workbench

Izabelle Humes, Cathy Shyr, Moira Dillon, Zhongjie Liu, Jennifer Peterson, Chris St Jeor, Jacqueline Malkes, Hiral Master, Brandy Mapes, Romuladus Azuine, Nakia Mack, Bassent Abdelbary, Joyonna Gamble-George, Emily Goldmann, Stephanie Cook, Fatemeh Choupani, Rubin Baskir, Sydney McMaster, Chris Lunt, Karriem WatsonMinnkyong Lee, Sophie Schwartz, Ruchi Munshi, David Glazer, Eric Banks, Anthony Philippakis, Melissa Basford, Dan Roden, Paul A. Harris

Global Public Health

Research output: Contribution to journal › Article › peer-review

Abstract

OBJECTIVES: The All of Us Research Program is a precision medicine initiative aimed at establishing a vast, diverse biomedical database accessible through a cloud-based data analysis platform, the Researcher Workbench (RW). Our goal was to empower the research community by co-designing the implementation of SAS in the RW alongside researchers to enable broader use of All of Us data. MATERIALS AND METHODS: Researchers from various fields and with different SAS experience levels participated in co-designing the SAS implementation through user experience interviews. RESULTS: Feedback and lessons learned from user testing informed the final design of the SAS application. DISCUSSION: The co-design approach is critical for reducing technical barriers, broadening All of Us data use, and enhancing the user experience for data analysis on the RW. CONCLUSION: Our co-design approach successfully tailored the implementation of the SAS application to researchers' needs. This approach may inform future software implementations on the RW.

Original language	English (US)
Pages (from-to)	2994-3000
Number of pages	7
Journal	Journal of the American Medical Informatics Association : JAMIA
Volume	31
Issue number	12
DOIs	https://doi.org/10.1093/jamia/ocae216
State	Published - Dec 1 2024

Keywords

data analysis
data ecosystem
diversity
precision medicine
software

ASJC Scopus subject areas

Health Informatics

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10.1093/jamia/ocae216

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Humes, I., Shyr, C., Dillon, M., Liu, Z., Peterson, J., Jeor, C. S., Malkes, J., Master, H., Mapes, B., Azuine, R., Mack, N., Abdelbary, B., Gamble-George, J., Goldmann, E., Cook, S., Choupani, F., Baskir, R., McMaster, S., Lunt, C., ... Harris, P. A. (2024). Empowering the biomedical research community: Innovative SAS deployment on the All of Us Researcher Workbench. Journal of the American Medical Informatics Association : JAMIA, 31(12), 2994-3000. https://doi.org/10.1093/jamia/ocae216

Humes, I, Shyr, C, Dillon, M, Liu, Z, Peterson, J, Jeor, CS, Malkes, J, Master, H, Mapes, B, Azuine, R, Mack, N, Abdelbary, B, Gamble-George, J, Goldmann, E, Cook, S, Choupani, F, Baskir, R, McMaster, S, Lunt, C, Watson, K, Lee, M, Schwartz, S, Munshi, R, Glazer, D, Banks, E, Philippakis, A, Basford, M, Roden, D & Harris, PA 2024, 'Empowering the biomedical research community: Innovative SAS deployment on the All of Us Researcher Workbench', Journal of the American Medical Informatics Association : JAMIA, vol. 31, no. 12, pp. 2994-3000. https://doi.org/10.1093/jamia/ocae216

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abstract = "OBJECTIVES: The All of Us Research Program is a precision medicine initiative aimed at establishing a vast, diverse biomedical database accessible through a cloud-based data analysis platform, the Researcher Workbench (RW). Our goal was to empower the research community by co-designing the implementation of SAS in the RW alongside researchers to enable broader use of All of Us data. MATERIALS AND METHODS: Researchers from various fields and with different SAS experience levels participated in co-designing the SAS implementation through user experience interviews. RESULTS: Feedback and lessons learned from user testing informed the final design of the SAS application. DISCUSSION: The co-design approach is critical for reducing technical barriers, broadening All of Us data use, and enhancing the user experience for data analysis on the RW. CONCLUSION: Our co-design approach successfully tailored the implementation of the SAS application to researchers' needs. This approach may inform future software implementations on the RW.",

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author = "Izabelle Humes and Cathy Shyr and Moira Dillon and Zhongjie Liu and Jennifer Peterson and Jeor, {Chris St} and Jacqueline Malkes and Hiral Master and Brandy Mapes and Romuladus Azuine and Nakia Mack and Bassent Abdelbary and Joyonna Gamble-George and Emily Goldmann and Stephanie Cook and Fatemeh Choupani and Rubin Baskir and Sydney McMaster and Chris Lunt and Karriem Watson and Minnkyong Lee and Sophie Schwartz and Ruchi Munshi and David Glazer and Eric Banks and Anthony Philippakis and Melissa Basford and Dan Roden and Harris, {Paul A.}",

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AU - Liu, Zhongjie

AU - Peterson, Jennifer

AU - Jeor, Chris St

AU - Malkes, Jacqueline

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AU - Mapes, Brandy

AU - Azuine, Romuladus

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AU - Abdelbary, Bassent

AU - Gamble-George, Joyonna

AU - Goldmann, Emily

AU - Cook, Stephanie

AU - Choupani, Fatemeh

AU - Baskir, Rubin

AU - McMaster, Sydney

AU - Lunt, Chris

AU - Watson, Karriem

AU - Lee, Minnkyong

AU - Schwartz, Sophie

AU - Munshi, Ruchi

AU - Glazer, David

AU - Banks, Eric

AU - Philippakis, Anthony

AU - Basford, Melissa

AU - Roden, Dan

AU - Harris, Paul A.

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Empowering the biomedical research community: Innovative SAS deployment on the All of Us Researcher Workbench

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Keywords

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