Encapsulation of biomolecules with programmable concentrations in microdroplets using electrokinetic concentrator

Yong Ak Song, Aniruddh Sarkar, Jongyoon Han

Research output: Contribution to conferencePaperpeer-review

Abstract

In this work, we describe a microfluidic device for the encapsulation of electrokinetically concentrated biomolecules in microdroplets and microparticles. We demonstrate the encapsulation of molecules and nanoparticles such as quantum dots into water-in-oil droplets and porous gel particles with on-the-fly adjustable concentrations by combining electrokinetic trapping and two-phase droplet generation in a single chip. Once in the droplets, the molecules and nanoparticles can then undergo chemical reactions or be delivered anywhere on the chip while maintaining programmed concentrations without dispersion loss over long time and distance scales.

Original languageEnglish (US)
Pages1420-1422
Number of pages3
StatePublished - 2008
Event12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States
Duration: Oct 12 2008Oct 16 2008

Other

Other12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
CountryUnited States
CitySan Diego, CA
Period10/12/0810/16/08

Keywords

  • Droplet
  • Electrokinetic concentration
  • World-to-chip interface

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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