Abstract
In this work, we describe a microfluidic device for the encapsulation of electrokinetically concentrated biomolecules in microdroplets and microparticles. We demonstrate the encapsulation of molecules and nanoparticles such as quantum dots into water-in-oil droplets and porous gel particles with on-the-fly adjustable concentrations by combining electrokinetic trapping and two-phase droplet generation in a single chip. Once in the droplets, the molecules and nanoparticles can then undergo chemical reactions or be delivered anywhere on the chip while maintaining programmed concentrations without dispersion loss over long time and distance scales.
Original language | English (US) |
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Pages | 1420-1422 |
Number of pages | 3 |
State | Published - 2008 |
Event | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: Oct 12 2008 → Oct 16 2008 |
Other
Other | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 |
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Country/Territory | United States |
City | San Diego, CA |
Period | 10/12/08 → 10/16/08 |
Keywords
- Droplet
- Electrokinetic concentration
- World-to-chip interface
ASJC Scopus subject areas
- Chemical Engineering (miscellaneous)
- Bioengineering