Enhancement of cancerous/normal tissue contrast via combined white light and fluorescence image processing: Initial investigation ex vivo

Angelos A. Kalitzeos, Azhar Zam, Florian Stelzle, Eckhart G. Hahn, Martin Raithel, Alexandre Douplik

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In the current study we try to optimise the cancerous/normal tissue contrast perception using white light and autofluorescence image processing. We deconvolved the RGB channels of both white light and autofluorescence images pixel by pixel and pointed out the best contrast enhancement technique, manipulating each channel seperately. By using false-color mapping according to a particular Look-Up Table, the borders between normal and cancerous area of the tissue are better delineated. Cancer tissue identification was confirmed by the histological examination that followed our investigation.

Original languageEnglish (US)
Title of host publicationEuropean Conference on Biomedical Optics, ECBO 2009
PublisherOptical Society of America
ISBN (Print)9780819476432
StatePublished - 2009
EventEuropean Conference on Biomedical Optics, ECBO 2009 - Munich, Germany
Duration: Jun 14 2009Jun 18 2009

Publication series

NameOptics InfoBase Conference Papers
ISSN (Electronic)2162-2701

Conference

ConferenceEuropean Conference on Biomedical Optics, ECBO 2009
Country/TerritoryGermany
CityMunich
Period6/14/096/18/09

Keywords

  • Autofluorescence
  • Clinical applications
  • Endoscopic imaging
  • Image processing

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics

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