To the Editor: Gangarosa and Merson (N Engl J Med 296:1210, 1977) conclude that “routine serogrouping of Esch. coli in sporadic cases of diarrhea using commercial antiserums#x2026;is#x2026;useless.” They review studies relating Esch. coli of the traditional enteropathogenic serotypes (EPEC) to diarrhea. Seven of these reports, published from 1950 to 1961, form the entire epidemiologic evidence “refuting” the virulence of EPEC.1 2 3 4 5 6 7 We wonder whether the results of these studies, especially when their methods are scrutinized, support the conclusions drawn, and we question their relevance to serogrouping in 1977. In one study, transient and sometimes asymptomatic infection with EPEC was found in.
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