TY - JOUR
T1 - Estimating genetic and environmental influences on depressive symptoms in adolescence
T2 - Differing effects on higher and lower levels of symptoms
AU - Rende, Richard
AU - Slomkowski, Cheryl
AU - Lloyd-Richardson, Elizabeth
AU - Stroud, Laura
AU - Niaura, Raymond
N1 - Funding Information:
This research uses data from Add Health, a program project designed by J. Richard Udry, Peter S. Bearman, and Kathleen Mullan Harris and funded by Grant P01–HD31921 from the National Institute of Child Health and Human Development, with cooperative funding from 17 other agencies. Special acknowledgment is due Ronald R. Rindfuss and Barbara Entwisle for assistance in the original design. Persons interested in obtaining data files from Add Health should contact Add Health, Carolina Population Center, 123 W. Franklin Street, Chapel Hill, NC 27516–2524 (www.cpc.unc. edu/addhealth/contract.html). Additional support was provided by National Institutes of Health Grant MH01559 to Richard Rende.
PY - 2006
Y1 - 2006
N2 - We estimate the relative effect sizes of genetic and environmental influences on both higher and lower levels of depressive symptoms with attention to persistence over a 1-year period in the genetically informative subsample of adolescents participating in the National Longitudinal Study of Adolescent Health (Add Health). Shared environmental effects were significant for persistent higher levels of depressive symptoms but not nonpersistent symptoms. Genetic effects were significant for both persistent and nonpersistent lower levels of depressive symptoms. Nongenetic factors that promote similarity between siblings for high levels of depressive symptoms are important and should be considered in both etiological and applied research. Genetic contributions to lack of susceptibility to depression should be considered in biological models of depression suppression.
AB - We estimate the relative effect sizes of genetic and environmental influences on both higher and lower levels of depressive symptoms with attention to persistence over a 1-year period in the genetically informative subsample of adolescents participating in the National Longitudinal Study of Adolescent Health (Add Health). Shared environmental effects were significant for persistent higher levels of depressive symptoms but not nonpersistent symptoms. Genetic effects were significant for both persistent and nonpersistent lower levels of depressive symptoms. Nongenetic factors that promote similarity between siblings for high levels of depressive symptoms are important and should be considered in both etiological and applied research. Genetic contributions to lack of susceptibility to depression should be considered in biological models of depression suppression.
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U2 - 10.1207/s15374424jccp3502_7
DO - 10.1207/s15374424jccp3502_7
M3 - Article
C2 - 16597219
AN - SCOPUS:33646543383
VL - 35
SP - 237
EP - 243
JO - Journal of clinical child psychology
JF - Journal of clinical child psychology
SN - 1537-4416
IS - 2
ER -