TY - JOUR
T1 - Evaluation of collagen-based membranes for guided bone regeneration, by three-dimensional computerized microtomography
AU - Coelho, Paulo Guilherme
AU - Giro, Gabriela
AU - Kim, Wanki
AU - Granato, Rodrigo
AU - Marin, Charles
AU - Bonfante, Estevam Augusto
AU - Bonfante, Samara
AU - Lilin, Thomas
AU - Suzuki, Marcelo
N1 - Funding Information:
Supported in part by Osteogenics (Lubbock, Texas), the Oral and Maxillofacial Surgery division at the Federal University of Santa Catarina (Brazil), and the New York University Summer Research Program (Wanki Kim).
PY - 2012/10
Y1 - 2012/10
N2 - Objective: The aim of this study was to evaluate the use of a collagen-based membrane compared with no treatment on guided bone regeneration by 3-dimensional computerized microtomography (μCT). Study Design: Defects were created between the mesial and distal premolar roots of the second and third premolars (beagle dogs; n = 8). A collagen-based membrane (Vitala; Osteogenics Biomedical Inc., TX, USA) was placed in one of the defects (membrane group; n = 16), and the other was left untreated (no-membrane group; n = 16). Left and right sides provided healing samples for 2 and 16 weeks. Three-dimensional bone architecture was acquired by μCT and categorized as fully regenerated (F, bone height and width) or nonregenerated (N). Results: Chi-square tests (95% level of significance) showed that tooth did not have an effect on outcome (P =.5). Significantly higher F outcomes were observed at 16 weeks than 2 weeks (P =.008) and in membrane group than in no-membrane group (P =.008). Conclusions: The collagen-based membrane influenced bone regeneration at the furcation.
AB - Objective: The aim of this study was to evaluate the use of a collagen-based membrane compared with no treatment on guided bone regeneration by 3-dimensional computerized microtomography (μCT). Study Design: Defects were created between the mesial and distal premolar roots of the second and third premolars (beagle dogs; n = 8). A collagen-based membrane (Vitala; Osteogenics Biomedical Inc., TX, USA) was placed in one of the defects (membrane group; n = 16), and the other was left untreated (no-membrane group; n = 16). Left and right sides provided healing samples for 2 and 16 weeks. Three-dimensional bone architecture was acquired by μCT and categorized as fully regenerated (F, bone height and width) or nonregenerated (N). Results: Chi-square tests (95% level of significance) showed that tooth did not have an effect on outcome (P =.5). Significantly higher F outcomes were observed at 16 weeks than 2 weeks (P =.008) and in membrane group than in no-membrane group (P =.008). Conclusions: The collagen-based membrane influenced bone regeneration at the furcation.
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U2 - 10.1016/j.oooo.2011.11.032
DO - 10.1016/j.oooo.2011.11.032
M3 - Article
C2 - 22819460
AN - SCOPUS:84866405654
SN - 2212-4403
VL - 114
SP - 437
EP - 443
JO - Oral Surgery Oral Medicine and Oral Pathology
JF - Oral Surgery Oral Medicine and Oral Pathology
IS - 4
ER -