TY - JOUR
T1 - Evaluation of collagen-based membranes for guided bone regeneration, by three-dimensional computerized microtomography
AU - Coelho, Paulo Guilherme
AU - Giro, Gabriela
AU - Kim, Wanki
AU - Granato, Rodrigo
AU - Marin, Charles
AU - Bonfante, Estevam Augusto
AU - Bonfante, Samara
AU - Lilin, Thomas
AU - Suzuki, Marcelo
PY - 2012/10
Y1 - 2012/10
N2 - Objective: The aim of this study was to evaluate the use of a collagen-based membrane compared with no treatment on guided bone regeneration by 3-dimensional computerized microtomography (μCT). Study Design: Defects were created between the mesial and distal premolar roots of the second and third premolars (beagle dogs; n = 8). A collagen-based membrane (Vitala; Osteogenics Biomedical Inc., TX, USA) was placed in one of the defects (membrane group; n = 16), and the other was left untreated (no-membrane group; n = 16). Left and right sides provided healing samples for 2 and 16 weeks. Three-dimensional bone architecture was acquired by μCT and categorized as fully regenerated (F, bone height and width) or nonregenerated (N). Results: Chi-square tests (95% level of significance) showed that tooth did not have an effect on outcome (P =.5). Significantly higher F outcomes were observed at 16 weeks than 2 weeks (P =.008) and in membrane group than in no-membrane group (P =.008). Conclusions: The collagen-based membrane influenced bone regeneration at the furcation.
AB - Objective: The aim of this study was to evaluate the use of a collagen-based membrane compared with no treatment on guided bone regeneration by 3-dimensional computerized microtomography (μCT). Study Design: Defects were created between the mesial and distal premolar roots of the second and third premolars (beagle dogs; n = 8). A collagen-based membrane (Vitala; Osteogenics Biomedical Inc., TX, USA) was placed in one of the defects (membrane group; n = 16), and the other was left untreated (no-membrane group; n = 16). Left and right sides provided healing samples for 2 and 16 weeks. Three-dimensional bone architecture was acquired by μCT and categorized as fully regenerated (F, bone height and width) or nonregenerated (N). Results: Chi-square tests (95% level of significance) showed that tooth did not have an effect on outcome (P =.5). Significantly higher F outcomes were observed at 16 weeks than 2 weeks (P =.008) and in membrane group than in no-membrane group (P =.008). Conclusions: The collagen-based membrane influenced bone regeneration at the furcation.
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U2 - 10.1016/j.oooo.2011.11.032
DO - 10.1016/j.oooo.2011.11.032
M3 - Article
C2 - 22819460
AN - SCOPUS:84866405654
VL - 114
SP - 437
EP - 443
JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
JF - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
SN - 2212-4403
IS - 4
ER -