Evolution of the protein repertoire

Cyrus Chothia; Julian Gough; Christine Vogel; Sarah A. Teichmann

doi:10.1126/science.1085371

Evolution of the protein repertoire

Cyrus Chothia, Julian Gough, Christine Vogel, Sarah A. Teichmann

Biology and Genomics

Research output: Contribution to journal › Review article › peer-review

Abstract

Most proteins have been formed by gene duplication, recombination, and divergence. Proteins of known structure can be matched to about 50% of genome sequences, and these data provide a quantitative description and can suggest hypotheses about the origins of these processes.

Original language	English (US)
Pages (from-to)	1701-1703
Number of pages	3
Journal	Science
Volume	300
Issue number	5626
DOIs	https://doi.org/10.1126/science.1085371
State	Published - Jun 13 2003

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abstract = "Most proteins have been formed by gene duplication, recombination, and divergence. Proteins of known structure can be matched to about 50% of genome sequences, and these data provide a quantitative description and can suggest hypotheses about the origins of these processes.",

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AU - Chothia, Cyrus

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AU - Vogel, Christine

AU - Teichmann, Sarah A.

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Evolution of the protein repertoire

Abstract

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