Evolutionary divergence of AP-PCR (RAPD) patterns

Luis Espinasa, Richard Borowsky

Research output: Contribution to journalArticlepeer-review


Rates at which AP-PCR patterns diverge among isolated taxa were examined to test whether they exhibit clocklike regularity. The results showed that rates of divergence differed significantly among the groups examined (primates, antelopes, and Hawaiian Drosophila grimshawi). Therefore, AP-PCR divergence rates cannot be used as a 'universal clock' with an invariant rate in all animals. Nevertheless, within each group, a strong relationship existed between degree of AP-PCR pattern divergence and time since separation of isolated taxa. Thus, AP-PCR divergence may prove useful for dating evolutionary events if calibrated within a more limited taxon.

Original languageEnglish (US)
Pages (from-to)408-414
Number of pages7
JournalMolecular Biology and Evolution
Issue number4
StatePublished - Apr 1998


  • AP-PCR
  • Clocklike behavior
  • Gene hornology
  • Phylogeny
  • RAPD

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics


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