Exploring a wider range of Mg-Ca-Zn metallic glass as biocompatible alloys using combinatorial sputtering

Jinyang Li; Forrest S. Gittleson; Yanhui Liu; Jingbei Liu; Ayomiposi M. Loye; Lyndsey McMillon-Brown; Themis R. Kyriakides; Jan Schroers; André D. Taylor

doi:10.1039/c7cc02733h

Exploring a wider range of Mg-Ca-Zn metallic glass as biocompatible alloys using combinatorial sputtering

Jinyang Li, Forrest S. Gittleson, Yanhui Liu, Jingbei Liu, Ayomiposi M. Loye, Lyndsey McMillon-Brown, Themis R. Kyriakides, Jan Schroers, André D. Taylor

Chemical and Biomolecular Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

In order to bypass the limitation of bulk metallic glasses fabrication, we synthesized thin film metallic glasses to study the corrosion characteristics of a wide atomic% composition range, Mg(35.9-63%)Ca(4.1-21%)Zn(17.9-58.3%), in simulated body fluid. We highlight a clear relationship between Zn content and corrosion current such that Zn-medium metallic glasses exhibit minimum corrosion. In addition, we found higher Zn content leads to a poor in vitro cell viability. These results showcase the benefit of evaluating a larger alloy compositional space to probe the limits of corrosion resistance and prescreen for biocompatible applications.

Original language	English (US)
Pages (from-to)	8288-8291
Number of pages	4
Journal	Chemical Communications
Volume	53
Issue number	59
DOIs	https://doi.org/10.1039/c7cc02733h
State	Published - 2017

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
General Chemistry
Ceramics and Composites
Metals and Alloys
Materials Chemistry
Surfaces, Coatings and Films
Catalysis

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10.1039/c7cc02733h

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title = "Exploring a wider range of Mg-Ca-Zn metallic glass as biocompatible alloys using combinatorial sputtering",

abstract = "In order to bypass the limitation of bulk metallic glasses fabrication, we synthesized thin film metallic glasses to study the corrosion characteristics of a wide atomic% composition range, Mg(35.9-63%)Ca(4.1-21%)Zn(17.9-58.3%), in simulated body fluid. We highlight a clear relationship between Zn content and corrosion current such that Zn-medium metallic glasses exhibit minimum corrosion. In addition, we found higher Zn content leads to a poor in vitro cell viability. These results showcase the benefit of evaluating a larger alloy compositional space to probe the limits of corrosion resistance and prescreen for biocompatible applications.",

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T1 - Exploring a wider range of Mg-Ca-Zn metallic glass as biocompatible alloys using combinatorial sputtering

AU - Li, Jinyang

AU - Gittleson, Forrest S.

AU - Liu, Yanhui

AU - Liu, Jingbei

AU - Loye, Ayomiposi M.

AU - McMillon-Brown, Lyndsey

AU - Kyriakides, Themis R.

AU - Schroers, Jan

AU - Taylor, André D.

PY - 2017

Y1 - 2017

N2 - In order to bypass the limitation of bulk metallic glasses fabrication, we synthesized thin film metallic glasses to study the corrosion characteristics of a wide atomic% composition range, Mg(35.9-63%)Ca(4.1-21%)Zn(17.9-58.3%), in simulated body fluid. We highlight a clear relationship between Zn content and corrosion current such that Zn-medium metallic glasses exhibit minimum corrosion. In addition, we found higher Zn content leads to a poor in vitro cell viability. These results showcase the benefit of evaluating a larger alloy compositional space to probe the limits of corrosion resistance and prescreen for biocompatible applications.

AB - In order to bypass the limitation of bulk metallic glasses fabrication, we synthesized thin film metallic glasses to study the corrosion characteristics of a wide atomic% composition range, Mg(35.9-63%)Ca(4.1-21%)Zn(17.9-58.3%), in simulated body fluid. We highlight a clear relationship between Zn content and corrosion current such that Zn-medium metallic glasses exhibit minimum corrosion. In addition, we found higher Zn content leads to a poor in vitro cell viability. These results showcase the benefit of evaluating a larger alloy compositional space to probe the limits of corrosion resistance and prescreen for biocompatible applications.

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Exploring a wider range of Mg-Ca-Zn metallic glass as biocompatible alloys using combinatorial sputtering

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